C. Lok

Publications216
h-index44
Citations6,502
Highly Influential Citations186
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Patency rates of the arteriovenous fistula for hemodialysis: a systematic review and meta-analysis.
BACKGROUND Advantages of the arteriovenous fistula (AVF), including long patency and few complications, were ascertained more than 2 decades ago and may not apply to the contemporary dialysis… Expand
  • 328
  • 12
Risk equation determining unsuccessful cannulation events and failure to maturation in arteriovenous fistulas (REDUCE FTM I).
Fistulas are the preferred permanent hemodialysis vascular access but a significant obstacle to increasing their prevalence is the fistula's high "failure to mature" (FTM) rate. This study aimed to… Expand
  • 367
  • 11
Fistula first initiative: advantages and pitfalls.
  • C. Lok
  • Medicine
  • Clinical journal of the American Society of…
  • 1 September 2007
### Vascular Access Care before 1997 The arteriovenous fistula (AVF) was first described and used as a reliable form of hemodialysis (HD) vascular access (VA) by Brescia et al. (1) in 1966.… Expand
  • 208
  • 11
Hemodialysis infection prevention with polysporin ointment.
Hemodialysis patients in whom permanent vascular access cannot be achieved are dependent on a central venous catheter. In such patients, catheter-related infections are a common and serious… Expand
  • 172
  • 8
Prevention of dialysis catheter malfunction with recombinant tissue plasminogen activator.
BACKGROUND The effectiveness of various solutions instilled into the central venous catheter lumens after each hemodialysis session (catheter locking solutions) to decrease the risk of catheter… Expand
  • 162
  • 8
Vascular access morbidity and mortality: trends of the last decade.
  • C. Lok, R. Foley
  • Medicine
  • Clinical journal of the American Society of…
  • 3 July 2013
During the past decade, clear trends in the types of incident and prevalent hemodialysis vascular access can be observed. There has been a steady increase and recent stabilizaton of patients… Expand
  • 119
  • 7
  • PDF
Arteriovenous fistula outcomes in the era of the elderly dialysis population.
BACKGROUND The growth of patients > or =65 years on hemodialysis is increasing. Guidelines recommend arteriovenous fistula (AVF) access but their outcomes in elderly patients are controversial. This… Expand
  • 173
  • 5
  • PDF
Increased hemodialysis catheter use in Canada and associated mortality risk: data from the Canadian Organ Replacement Registry 2001-2004.
BACKGROUND AND OBJECTIVES The 1999 Canadian vascular access guidelines recommend the fistula as the access of choice. The study describes the trends in hemodialysis access use, variation among… Expand
  • 134
  • 5
  • PDF
Prevention and management of catheter-related infection in hemodialysis patients.
Central venous catheter-related infections have been associated with high morbidity, mortality, and costs. Catheter use in chronic hemodialysis patients has been recognized as distinct from other… Expand
  • 134
  • 5
Trisodium citrate 4%--an alternative to heparin capping of haemodialysis catheters.
BACKGROUND Central venous catheters (CVCs) continue to be used at a high rate for dialysis access and are frequently complicated by thrombus-related malfunction. Prophylactic locking with an… Expand
  • 81
  • 5
  • PDF