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ETHOWATCHER: validation of a tool for behavioral and video-tracking analysis in laboratory animals
TLDR
A software developed to support ethography, object tracking and extraction of kinematic variables from digital video files of laboratory animals and on the detection of known behavioral effects of drugs is presented.
Repeated rat-forced swim test: Reducing the number of animals to evaluate gradual effects of antidepressants
TLDR
Repeated rat-FST seemed suitable to detect short and long term effects of selective serotonin reuptake inhibitors, or other ADT, thus reducing the number of animals used in the screenings of this type of compounds.
A proposal for refining the forced swim test in Swiss mice
TLDR
The method proposed here is able to distinguish antidepressants from stimulants of motor activity using Swiss mice in the FST and should reduce the number of mice used in preclinical evaluation of antidepressants.
Distribution and characterization of doublecortin-expressing cells and fibers in the brain of the adult pigeon (Columba livia)
TLDR
The VZ in the brain of adult pigeons seems to have rapidly dividing cells as putative progenitors of newborn neurons populating the forebrain, suggesting that the morphological turnover of forebrain circuits is an important mechanism for brain plasticity in avian species during adulthood.
Structure of the rat behaviour in the forced swimming test
TLDR
The present data suggest there are at least two different factors that grouped variables related to the behavioural despair in the FST and altered motor activity could be predicted by the frequency of climbing behaviour recorded inThe FST.
Enhanced dorsolateral periaqueductal gray activity counteracts the anxiolytic response to midazolam on the elevated plus-maze Trial 2 in rats
TLDR
The present results suggest that an increased activity of the dlPAG during Trial 2 would explain the lack of anxiolytic-like effect of drugs elicited by prior EPM test experience.
Antidepressant treatment reduces Fos-like immunoreactivity induced by swim stress in different columns of the periaqueductal gray matter
TLDR
Results indicate that neurons in the PAG are activated by uncontrollable stress and inhibitory action of antidepressants on this activity may be associated with the anti-immobility effects of these drugs in the FST.
Distribution of tryptophan hydroxylase-immunoreactive neurons in the brainstem and diencephalon of the pigeon (Columba livia)
TLDR
These cells correspond to dopamine- and melatonin-containing neurons previously found in the avian hypothalamus, and appear to be comparable to the mammalian TPH-ir hypothalamic A11-A13 catecholaminergic somata, suggesting that they may be a conserved attribute in the amniote medial hypothalamus.
Effects of acute and chronic fluoxetine treatments on restraint stress-induced Fos expression
TLDR
The results suggest that chronic fluoxetine treatment induce plastic changes that result in a different regional pattern of Fos expression in animals submitted to restraint stress.
Defensive behaviors and prosencephalic neurogenesis in pigeons (Columba livia) are affected by environmental enrichment in adulthood
TLDR
Enriched environment data suggest that enrichment favored behavioral inhibition and neurogenesis in the adult pigeons through different, parallel mechanisms.
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