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SOX2 contributes to melanoma cell invasion
The mechanisms of melanoma invasion are poorly understood despite extensive inquiry. SRY (sex determining region Y)-box 2 (SOX2) is an embryonic stem cell transcription factor that has recently beenExpand
Helicobacter pylori eradication prevents progression of gastric cancer in hypergastrinemic INS-GAS mice.
Helicobacter pylori infection results in chronic gastritis, which may progress to gastric cancer. In this study, we investigated the efficacy of H. pylori eradication in preventing the progression ofExpand
Wild-Type and Interleukin-10-Deficient Regulatory T Cells Reduce Effector T-Cell-Mediated Gastroduodenitis in Rag2−/− Mice, but Only Wild-Type Regulatory T Cells Suppress Helicobacter pylori Gastritis
ABSTRACT CD4+ CD45RBhi CD25− effector T cells (TE) promote Helicobacter pylori gastritis in mice, and CD4+ CD45RBlo CD25+ regulatory T cells (TR) are anti-inflammatory. Using adoptive transfer intoExpand
Heat shock factor 1 induces cancer stem cell phenotype in breast cancer cell lines
Heat shock factor 1 (HSF1) has long been recognized as the master transcription factor that regulates heat shock proteins (HSPs).  More recently HSF1 has been associated with a broader role inExpand
Vitamin C supplementation does not protect L‐gulono‐γ‐lactone oxidase‐deficient mice from Helicobacter pylori‐induced gastritis and gastric premalignancy
  • C. Lee, X. Wang, +7 authors J. Fox
  • Biology, Medicine
  • International journal of cancer
  • 7 November 2007
In human studies, low vitamin C intake has been associated with more severe Helicobacter pylori gastritis and a higher incidence of gastric cancer. However, vitamin C supplementation has not beenExpand
CD44/CD24 Expression in recurrent gastric cancer: a retrospective analysis
BackgroundTo correlate CD44/CD24 expression with gastric cancer recurrence and prognosis. Gastric cancer is the second leading cause of cancer mortality due to the high recurrence rate, of which theExpand
Nestin depletion induces melanoma matrix metalloproteinases and invasion
Matrix metalloproteinases (MMPs) are key biological mediators of processes as diverse as wound healing, embryogenesis, and cancer progression. Although MMPs may be induced through multiple signalingExpand
Combination of sulindac and antimicrobial eradication of Helicobacter pylori prevents progression of gastric cancer in hypergastrinemic INS-GAS mice.
Helicobacter pylori infection causes severe dysplasia manifested as gastrointestinal intraepithelial neoplasia (GIN) after 28 weeks post-H. pylori infection (WPI) in cancer-prone, hypergastrinemicExpand
Compositions et formulations pour le traitement des maladies de malabsorption et les affections inflammatoires des voies gastro-intestinales, leurs procédés de production et d'utilisation
Cette invention concerne des polypeptides nutritifs. Divers autres modes de realisation comprenant des acides nucleiques codant pour lesdits polypeptides, des micro-organismes recombines pour lesExpand
A Combination of Sulindac and Antimicrobial Eradication of H . pylori Prevents Progression of Gastric Cancer in Hypergastrinemic INS-GAS Mice
Helicobacter pylori infection causes severe dysplasia manifested as gastrointestinal intraepithelial neoplasia (GIN) after 28 weeks post H. pylori infection (WPI) in cancer-prone, hypergastrinemicExpand
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