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The behaviour and ecology of the zebrafish, Danio rerio
- Rowena Spence, G. Gerlach, C. Lawrence, C. Smith
- Biology, Medicine
- Biological reviews of the Cambridge Philosophical…
- 17 December 2007
The zebrafish Danio rerio, is an important model organism in developmental genetics, neurophysiology and biomedicine, but little is known about its natural ecology and behaviour. It is a small,… Expand
The husbandry of zebrafish (Danio rerio): A review
- C. Lawrence
- 14 September 2007
The zebrafish (Danio rerio) has recently emerged as a pre-eminent vertebrate biomedical research model. The same favorable characteristics that have contributed to its popularity as a model of human… Expand
Rapid growth and out-crossing promote female development in zebrafish (Danio rerio)
Sex determination in fishes is often enigmatic, a situation that is often made even more complex by the fact that the process of sexual differentiation in many species may be influenced by… Expand
A phase II study of temozolomide and bevacizumab in patients with advanced neuroendocrine tumors.
- M. Kulke, K. Stuart, +7 authors C. Fuchs
- Journal of clinical oncology : official journal…
- 20 June 2006
4044 Background: Inhibitors of the VEGF pathway have been shown to have activity in neuroendocrine tumors (NETs). Temozolomide (TMZ), an oral analog of dacarbazine is also active in this setting. We… Expand
Advances in zebrafish husbandry and management.
- C. Lawrence
- Medicine, Biology
- Methods in cell biology
The zebrafish has emerged over the past several decades to become a mainstream animal model. While the growth of the use of the fish in basic biomedical research has been characterized by innovation,… Expand
Zebrafish housing systems: a review of basic operating principles and considerations for design and functionality.
The strategies for housing zebrafish used in biomedical research have evolved considerably over the past three decades. To keep pace with the rapid expansion and development of the zebrafish model… Expand
The effects of feeding frequency on growth and reproduction in zebrafish (Danio rerio)
Abstract In the present study, we examined the effects of feeding regime on growth and reproductive performance in wild-type zebrafish (Danio rerio) maintained on a recirculating aquaculture system.… Expand
The effect of stocking densities on reproductive performance in laboratory zebrafish (Danio rerio).
Despite the growing popularity of the zebrafish model system, the optimal husbandry conditions for this animal are not well defined. The aim of this study was to examine the effect of stocking… Expand
The challenges of implementing pathogen control strategies for fishes used in biomedical research.
- C. Lawrence, D. Ennis, Claudia Harper, M. Kent, K. Murray, G. Sanders
- Medicine, Biology
- Comparative biochemistry and physiology…
Over the past several decades, a number of fish species, including the zebrafish, medaka, and platyfish/swordtail, have become important models for human health and disease. Despite the increasing… Expand
Generation time of zebrafish (Danio rerio) and medakas (Oryzias latipes) housed in the same aquaculture facility
The zebrafish and the medaka are both important model organisms in biomedical research. Both species are frequently characterized as having a generation time of approximately 2–4 months, but the… Expand