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Genotype–phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC
TLDR
The molecular and pathological classification of hepatocellular adenoma permits the identification of strong genotype–phenotype correlations and suggests that adenomas with β‐catenin activation have a higher risk of malignant transformation. Expand
Hepatocellular adenoma management and phenotypic classification: The Bordeaux experience
TLDR
There were noticeable clinical differences between HNF1α–inactivated HCA and IHCA; there was no increased risk of bleeding or HCC related to the number of HCAs; β‐catenin–activated HCAs are at higher risk of HCC. Expand
Corrigendum: High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions
Somatic mutations activating telomerase reverse-trancriptase promoter were recently identified in several tumour types. Here we identify frequent similar mutations in human hepatocellular carcinomasExpand
Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification.
TLDR
It is shown here that HCC phenotype is tightly associated to its molecular alterations and underlying oncogenic pathways, both at the pathological and molecular levels. Expand
Risk factors for anastomotic leakage after resection of rectal cancer
TLDR
The aim of this retrospective study was to evaluate the risk factors for clinical anastomotic leakage after anterior resection for cancer of the rectum. Expand
Hepatocellular adenomas: Magnetic resonance imaging features as a function of molecular pathological classification
TLDR
HNF‐1α–mutated HCAs and inflammatory HCAs were associated with specific MRI patterns related to diffuse fat repartition and sinusoidal dilatation, respectively. Expand
Low Rectal Cancer: Classification and Standardization of Surgery
TLDR
This study demonstrated that most patients with low rectal cancer can receive conservative surgery without compromising oncologic outcome, and proposed a new surgical classification that should be used to standardize surgery and increase sphincter-preserving surgery in low Rectal cancer. Expand
Perineal Transanal Approach: A New Standard for Laparoscopic Sphincter-Saving Resection in Low Rectal Cancer, a Randomized Trial
TLDR
Perineal rectal dissection reduces the risk of positive circumferential resection margin, as compared with the conventional abdominal dissection in low rectal cancer, which suggests the perineal Rectal Dissection as a new standard in laparoscopic sphincter-saving resection for low Rectal cancer. Expand
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions
Somatic mutations activating telomerase reverse-trancriptase promoter were recently identified in several tumour types. Here we identify frequent similar mutations in human hepatocellular carcinomasExpand
Over‐expression of glutamine synthetase in focal nodular hyperplasia: a novel easy diagnostic tool in surgical pathology
TLDR
This work investigated the use of GS as a marker in various clinical situations, in which FNH diagnosis had been firmly established, to determine its contribution to diagnosis. Expand
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