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Cellular bases of neocortical activation: modulation of neural oscillations by the nucleus basalis and endogenous acetylcholine
In the mammalian neocortex, the EEG reflects the state of behavioral arousal. The EEG undergoes a transformation, known as activation, during the transition from sleep to waking. Abundant evidenceExpand
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Fourier analysis of sinusoidally driven thalamocortical relay neurons and a minimal integrate-and-fire-or-burst model.
We performed intracellular recordings of relay neurons from the lateral geniculate nucleus of a cat thalamic slice preparation. We measured responses during both tonic and burst firing modes toExpand
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Nucleus reticularis neurons mediate diverse inhibitory effects in thalamus.
Detailed information regarding the contribution of individual gamma-aminobutyric acid (GABA)-containing inhibitory neurons to the overall synaptic activity of single postsynaptic cells is essentialExpand
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Absence of metabotropic glutamate receptor-mediated plasticity in the neocortex of fragile X mice
  • B. M. Wilson, C. L. Cox
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences
  • 13 February 2007
Fragile X syndrome is a common heritable form of mental retardation in humans. Recent neuroanatomical studies indicate an apparent immature appearance of neurons in fragile X syndrome patients andExpand
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Control of Dendritic Outputs of Inhibitory Interneurons in the Lateral Geniculate Nucleus
The thalamic relay to neocortex is dynamically gated. The inhibitory interneuron, which we have studied in the lateral geniculate nucleus, is important to this process. In addition to axonal outputs,Expand
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Are Articular Cartilage Lesions and Meniscus Tears Predictive of IKDC, KOOS, and Marx Activity Level Outcomes After Anterior Cruciate Ligament Reconstruction?
Background: Identifying risk factors for inferior outcomes after anterior cruciate ligament reconstruction (ACLR) is important for prognosis and future treatment. Hypothesis: Articular cartilageExpand
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Glutamate locally activates dendritic outputs of thalamic interneurons
The relay of information through thalamus to cortex is dynamically gated, as illustrated by the retinogeniculocortical pathway. Important to this is the inhibitory interneuron in the lateralExpand
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Circadian Rhythm of Redox State Regulates Excitability in Suprachiasmatic Nucleus Neurons
Diurnal metabolic changes in circadian clock neurons are coupled to changes in potassium channel activity. Daily rhythms of mammalian physiology, metabolism, and behavior parallel the day-nightExpand
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Heterogeneous axonal arborizations of rat thalamic reticular neurons in the ventrobasal nucleus
The γ‐aminobutyric acid (GABA)‐containing neurons of the thalamic reticular nucleus (nRt) are a major source of inhibitory innervation in dorsal thalamic nuclei. Individual nRt neurons wereExpand
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Action potentials reliably invade axonal arbors of rat neocortical neurons.
Neocortical pyramidal neurons have extensive axonal arborizations that make thousands of synapses. Action potentials can invade these arbors and cause calcium influx that is required forExpand
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