• Publications
  • Influence
Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids
TLDR
The results identify several novel loci associated with plasma lipids that are also associated with CAD and provide the foundation to develop a broader biological understanding of lipoprotein metabolism and to identify new therapeutic opportunities for the prevention of CAD. Expand
Longitudinal evidence that fatherhood decreases testosterone in human males
TLDR
It is suggested that T mediates tradeoffs between mating and parenting in humans, as seen in other species in which fathers care for young, and that T and reproductive strategy have bidirectional relationships in human males. Expand
Adipose tissue in human infancy and childhood: an evolutionary perspective.
  • C. Kuzawa
  • Biology, Medicine
  • American journal of physical anthropology
  • 1998
TLDR
Well-fed infants acquire peak fat reserves by an age of peak prevalence of malnutrition, infectious disease, and fat reserve depletion in less-buffered contexts, and childhood--characterized by minimal investment in the tissue--is a stage of reduced risk of energy stress. Expand
EMERGING AND RE-EMERGING INFECTIOUS DISEASES: The Third Epidemiologic Transition
We use an expanded framework of multiple epidemiologic transitions to review the issues of re/emerging infection. The first epidemiologic transition was associated with a rise in infectious diseasesExpand
Epigenetics and the embodiment of race: Developmental origins of US racial disparities in cardiovascular health
  • C. Kuzawa, E. Sweet
  • Medicine
  • American journal of human biology : the official…
  • 1 January 2009
TLDR
It is concluded that environmentally responsive phenotypic plasticity, in combination with the better‐studied acute and chronic effects of social‐environmental exposures, provides a more parsimonious explanation than genetics for the persistence of CVD disparities between members of socially imposed racial categories. Expand
Fetal origins of developmental plasticity: Are fetal cues reliable predictors of future nutritional environments?
  • C. Kuzawa
  • Biology, Medicine
  • American journal of human biology : the official…
  • 2005
TLDR
This review evaluates the postnatal adaptive significance of fetal developmental plasticity from the perspective of life history theory and evolutionary models of energy partitioning to suggest that the flow of nutrients reaching the fetus provides an integrated signal of nutrition as experienced by recent matrilineal ancestors. Expand
Worldwide allele frequencies of the human apolipoprotein E gene: climate, local adaptations, and evolutionary history.
TLDR
It is found that elevation did not improve predictive power, and an integrated measure of the cholesterol effect of multiple APOE alleles was less related to latitude than was epsilon4 alone, suggesting a link between past temperature and human APOE allele distribution. Expand
Prolonged myelination in human neocortical evolution
TLDR
Comparisons between chimpanzees and humans suggest that the human-specific shift in the timing of cortical maturation during adolescence may have implications for vulnerability to certain psychiatric disorders. Expand
Metabolic correlates of hominid brain evolution.
TLDR
Paleontological evidence indicates that the rapid brain evolution observed with the emergence of Homo erectus at approximately 1.8 million years ago was likely associated with important changes in diet and body composition. Expand
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
TLDR
The number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking, are extended and highlight genetic links between fetal growth and postnatal growth and metabolism. Expand
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