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Mutations in the STK11 Gene Characterize Minimal Deviation Adenocarcinoma of the Uterine Cervix
Minimal deviation adenocarcinoma (MDA) is a well-differentiated variant of mucinous adenocarcinoma of the uterine cervix and is found relatively infrequently in the general population. However, MDAExpand
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Clonal Analysis and Mutations in the PTEN and the K-ras Genes in Endometrial Hyperplasia
The patterns of X chromosome inactivation and mutations of PTEN and K-ras were evaluated in cases of endometrial hyperplasia to determine the presence of potentially premalignant neoplastic versusExpand
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Antibody to annexin V has anti‐phospholipid and lupus anticoagulant properties
Anti‐annexin V (anti‐ANXV) IgG and lupus anticoagulant (LAC) were both shown to be capable of inducing apoptosis in umbilical vein endothelial cells [Nakamura et al.:Biochem Biophys Res CommunExpand
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Concurrent Weekly Nedaplatin, External Beam Radiotherapy and High-Dose-Rate Brachytherapy in Patients with FIGO Stage IIIb Cervical Cancer: A Comparison with a Cohort Treated by Radiotherapy Alone
Objectives: The aim of this study was to evaluate whether nedaplatin-based concurrent chemoradiotherapy (CCRT) using high-dose-rate intracavitary brachytherapy (HDR-ICBT) is superior to radiotherapyExpand
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Chemotherapy for endometrial carcinoma (GOGO-EM1 study): TEC (paclitaxel, epirubicin, and carboplatin) is an effective remission-induction and adjuvant therapy
BackgroundTAP chemotherapy (paclitaxel, doxorubicin, and cisplatin) is effective for advanced and recurrent endometrial carcinoma, but has occasional severe toxicity. TEC chemotherapy (paclitaxel,Expand
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Prognostic significance of p53 mutation in suboptimally resected advanced ovarian carcinoma treated with the combination chemotherapy of paclitaxel and carboplatin.
The prognostic significance of p53 mutation, microsattelite instability and DNA mismatch protein hMLH1 expression in suboptimally resected advanced ovarian carcinoma treated with the combinationExpand
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fhit alterations in endometrial carcinoma and hyperplasia
The fhit (fragile histidine triad) gene on chromosome 3p14.2 is a candidate tumour‐suppressor gene; its abnormal transcripts are detected in several human cancers. To define the role of the fhit geneExpand
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Hemoperitoneum as the First Manifestation of Acute Leukemia
A rare case of a 31-year-old woman is reported who had massive intraperitoneal bleeding caused by ovarian hemorrhage as the first manifestation of acute leukemia. Preoperative laboratory findingsExpand
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