C. Kirvan

Publications8
h-index6
Citations788
Highly Influential Citations29
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Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham chorea
Streptococcus pyogenes–induced acute rheumatic fever (ARF) is one of the best examples of postinfectious autoimmunity due to molecular mimicry between host and pathogen. Sydenham chorea is the major… Expand
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Streptococcal mimicry and antibody-mediated cell signaling in the pathogenesis of Sydenham's chorea
Recent evidence suggests that the pathogenesis of Sydenham's chorea following group A streptococcal infection is due to antibodies which develop due to the infection and infiltrate the brain and… Expand
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Antibody-mediated neuronal cell signaling in behavior and movement disorders
Behavioral and movement disorders may have antibody responses where mimicry and signal transduction may lead to neuropsychiatric abnormalities. In our study, antibodies in pediatric autoimmune… Expand
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Tubulin Is a Neuronal Target of Autoantibodies in Sydenham’s Chorea1
Sydenham’s chorea is a CNS disorder and sequela of group A streptococcal infection where deposition of Abs in brain may result in movement and neuropsychiatric abnormalities. We studied human mAbs… Expand
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Triple Aim in Canada: developing capacity to lead to better health, care and cost
Abstract Quality problem Many modern health systems strive for ‘Triple Aim’ (TA)—better health for populations, improved experience of care for patients and lower costs of the system, but note… Expand
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Identification of Streptococcal M-Protein Cardiopathogenic Epitopes in Experimental Autoimmune Valvulitis
The M protein of rheumatogenic group A streptococci induces carditis and valvulitis in Lewis rats and may play a role in pathogenesis of rheumatic heart disease. To identify the epitopes of M5… Expand
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Autoantibodies in Sydenham's Chorea Tubulin Is a Neuronal Target of
Madeleine W. CunninghamChristine A. Kirvan, Carol J. Cox, Susan E. Swedo andhttp://www.jimmunol.org/content/178/11/7412J Immunol€2007; 178:7412-7421;… Expand
Morvan線維性舞踏病におけるAChR,シナプス組織化蛋白質,タイチンと他の筋肉蛋白質に対する抗体 | 文献情報 | J-GLOBAL 科学技術総合リンクセンター