• Publications
  • Influence
Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia
TLDR
Cellular and molecular consequences of physioxia versus normoxia and hypoxia, and the role of microRNAs in Hypoxia‐dependent regulations are summarized. Expand
ROS implication in a new antitumor strategy based on non‐thermal plasma
TLDR
The potential of NTP to generate ROS renders this strategy particularly promising in the context of tumor treatment, as well as in vitro and in vivo experiments. Expand
Overexpression of heme oxygenase-1 in murine melanoma: increased proliferation and viability of tumor cells, decreased survival of mice.
TLDR
Heme oxygenase-1 overexpression increased viability, proliferation, and angiogenic potential of melanoma cells, augmented metastasis, and decreased survival of tumor-bearing mice, suggesting that induction of HO-1 may be detrimental in anti-cancer therapy of melan cancer. Expand
Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
TLDR
It is concluded that 5,6-Dimethylxanthenone-4-acetic acid can induce vascular endothelial cell apoptosis in some murine and human tumours and appears to be independent of tumour necrosis factor induction. Expand
Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia.
TLDR
The potential role of hypoxia, a major feature of most solid tumors, within the tumor microenvironment and how it contributes to immune resistance and immune suppression/tolerance and can be detrimental to antitumor effector cell functions is outlined. Expand
Human keratinocyte membrane lectins: characterization and modulation of their expression by cytokines
TLDR
The detection of cell surface sugar specific receptors: membrane lectins was undertook in an attempt to identify cell surface molecules involved in recognition phenomena between cells such as keratinocytes and melanocytes and putatively target biological responses modifiers to keratinocyte. Expand
Heme Oxygenase-1 Accelerates Cutaneous Wound Healing in Mice
TLDR
Induction of HO-1 in wounded skin was relatively weak and delayed in diabetic mice, in which also angiogenesis and wound closure were impaired, and may be associated with delayedHO-1 upregulation and can be improved by HO- 1 gene transfer. Expand
Interplay between heme oxygenase-1 and miR-378 affects non-small cell lung carcinoma growth, vascularization, and metastasis.
TLDR
In vitro and in vivo data indicate that the interplay between HMOX1 and miR-378 significantly modulates NSCLC progression and angiogenesis, suggesting miR -378 as a new therapeutic target. Expand
Endothelial cells as key determinants of the tumor microenvironment: interaction with tumor cells, extracellular matrix and immune killer cells.
TLDR
The role played by circulating endothelial progenitor cells is addressed and their features and mechanism of recruitment to the tumor microenvironment and their role in tumor angiogenesis are illustrated. Expand
Nitric oxide modulates the expression of endothelial cell adhesion molecules involved in angiogenesis and leukocyte recruitment.
TLDR
During angiogenesis and leukocyte recruitment, NO(•) regulates cell interactions by controlling adhesion molecule expression and subsequently cell adhesion, reflecting the functions of the tissue they originate from. Expand
...
1
2
3
4
5
...