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Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America
TLDR
This guideline updates recommendations regarding epidemiology, diagnosis, treatment, and infection control and environmental management of Clostridium difficile. Expand
Clostridium difficile--more difficult than ever.
TLDR
Recent changes in the epidemiology of C. difficile have become both more prevalent and more virulent and the use of new antibiotics, probiotics, immunotherapy, and even bacteriotherapy is discussed. Expand
ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease
TLDR
Given the incomplete response of many patients to a GFD-free diet as well as the difficulty of adherence to the GFD over the long term, development of new effective therapies for symptom control and reversal of inflammation and organ damage are needed. Expand
Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of
TLDR
This guideline updates recommendations regarding epidemiology, diagnosis, treatment, infection prevention, and environmental management on Clostridium difficile infection in adults and includes recommendations for children. Expand
Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile.
TLDR
A conservative estimate of the cost of this disease in the United States exceeds $1.1 billion per year after adjustment for age, comorbidity, and disease severity. Expand
The Oslo definitions for coeliac disease and related terms
TLDR
A multidisciplinary task force of 16 physicians from seven countries used the electronic database PubMed to review the literature for CD-related terms and suggested a definition for each term, followed by feedback through a web survey on definitions and discussions during a meeting in Oslo. Expand
A mouse model of Clostridium difficile-associated disease.
TLDR
A mouse model of antibiotic-induced C. difficile-associated disease (CDAD) that more closely resembles human disease is developed and will be valuable in testing new treatments, examining disease pathogenesis, and elucidating mechanisms of protective immunity. Expand
Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A.
TLDR
There is no evidence of immune protection against colonization by C. difficile in hospitalized patients who were receiving antibiotics, but after colonization there is an association between a systemic anamnestic response to toxin A, as evidenced by increased serum levels of IgG antibody against toxins A, and asymptomatic carriage of C.difficile. Expand
Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea
TLDR
A serum antibody response to toxin A, during an initial episode of C. difficile diarrhoea, is associated with protection against recurrence, and this response isomersally associated with higher concentrations of serum IgM against toxin A. Expand
Clostridium difficile infection.
TLDR
Diarrhea and colitis usually improve within three days after a patient starts taking metronidazole or vancomycin, but 20% suffer a relapse of diarrhea when these agents are discontinued. Expand
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