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(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans.
- H. Schroeter, C. Heiss, +7 authors M. Kelm
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 24 January 2006
Epidemiological and medical anthropological investigations suggest that flavanol-rich foods exert cardiovascular health benefits. Endothelial dysfunction, a prognostically relevant key event in… Expand
Sustained benefits in vascular function through flavanol-containing cocoa in medicated diabetic patients a double-masked, randomized, controlled trial.
- J. Balzer, T. Rassaf, +8 authors M. Kelm
- Journal of the American College of Cardiology
- 3 June 2008
OBJECTIVES Our goal was to test feasibility and efficacy of a dietary intervention based on daily intake of flavanol-containing cocoa for improving vascular function of medicated diabetic patients.… Expand
Probiotics and immunity
- A. Borchers, C. Selmi, F. Meyers, C. Keen, M. E. Gershwin
- Journal of Gastroenterology
- 22 January 2009
Probiotics are defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host, including the gastrointestinal tract. While this beneficial effect was… Expand
Copper, oxidative stress, and human health.
Copper (Cu), a redox active metal, is an essential nutrient for all species studied to date. During the past decade, there has been increasing interest in the concept that marginal deficits of this… Expand
Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation status.
- D. Rein, S. Lotito, R. Holt, C. Keen, H. Schmitz, C. Fraga
- Chemistry, Medicine
- The Journal of nutrition
- 1 August 2000
Diets that are rich in plant foods have been associated with a decreased risk for specific disease processes and certain chronic diseases. In addition to essential macronutrients and micronutrients,… Expand
Lyme disease: a rigorous review of diagnostic criteria and treatment.
Lyme disease was originally identified in Lyme, Connecticut, based upon an unusual cluster of what appeared to be patients with juvenile rheumatoid arthritis. It was subsequently identified as a new… Expand
Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa.
- R. Holt, S. Lazarus, +6 authors C. Keen
- Chemistry, Medicine
- The American journal of clinical nutrition
- 1 October 2002
BACKGROUND Epidemiologic studies have linked flavonoid-rich foods with a reduced risk of cardiovascular mortality. Some cocoas are flavonoid-rich and contain the monomeric flavanols (-)-epicatechin… Expand
Regular Consumption of a Flavanol-rich Chocolate can Improve Oxidant Stress in Young Soccer Players
- C. Fraga, L. Actis-Goretta, +5 authors C. Keen
- Clinical & developmental immunology
- 1 March 2005
The consumption of a diet rich in certain flavonoids, including the flavanol sub-class, has been associated with a reduced risk for vascular disease. We evaluated the effects of the regular… Expand
Mushrooms, tumors, and immunity.
- A. Borchers, J. Stern, R. M. Hackman, C. Keen, M. E. Gershwin
- Medicine, Biology
- Proceedings of the Society for Experimental…
- 1 August 1999
Medicinal properties have been attributed to mushrooms for thousands of years. Mushroom extracts are widely sold as nutritional supplements and touted as beneficial for health. Yet, there has not… Expand
Cocoa and chocolate flavonoids: implications for cardiovascular health.
- F. Steinberg, Monica M Bearden, C. Keen
- Journal of the American Dietetic Association
- 1 February 2003
This paper offers a review of current scientific research regarding the potential cardiovascular health benefits of flavonoids found in cocoa and chocolate. Recent reports indicate that the main… Expand