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Chemical and biological investigations of a toxic plant from Central Africa, Magnistipula butayei subsp. montana.
Magnistipula butayei subsp. montana (Chrysobalanaceae) is known, in the Great Lakes Region, to possess toxicological properties. In this paper, we investigated the acute toxicity (dose levels 50-1600Expand
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Characterization of the neurotoxicity induced by the extract of Magnistipula butayei (Chrysobalanaceae) in rat: effects of a new natural convulsive agent.
This study was designed to document convulsant and neurotoxic properties of extracts of a tropical tree, Magnistipula butayei subsp. Montana, and to investigate the involvement of the glutamatergicExpand
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Validation of an analytical method for the determination in serum of psychotropic drugs by High-Performance Liquid Chromatography with Diode Array Detection
Background : Inter-individual variability in clinical response to psychotropic drugs remains problematic in management of mental illnesses. The patients differ in their ability to absorb, distribute,Expand
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The Use of Benzoyl-Dl-Arginine-Naphthylamide (Bana) Test as A Screening Test for Mother at Risk for Delivery of Pre-Term and Low Birth Weight in A Rwandan Population
Oral infections can act as the site of origin for dissemination of periodonto-bacteria and their toxins as well as induce inflammatory mechanisms to distant body sites, thus linking periodontalExpand
TDM of Psychotropic Drugs in Rwanda
The use of psychotropic medications in Rwanda is not limited to treatment of usual mental illnesses only, but these drugs are used also in management of some sequels of various atrocities experiencedExpand
Erratum to “Chemical and biological investigations of a toxic plant from Central Africa, Magnistipula butayei subsp. montana” [J. Ethnopharmacol. 103 (2006) 433–438]
Please note that a new botanical identification of the plant used in our study leads to the conclusion that the plant sample was Dichapetalum stuhlmannii Engler (synonym of D. michelsonii), alsoExpand
Transfer of high performance liquid chromatography with diode array detection method for determination in serum of psychotropic drugs
Background: The relevance of the determination of blood concentration levels of psychotropic drugs has been demonstrated in Rwanda. However, due to the lack of appropriate analytical methods, suchExpand
Determination of blood concentration levels of psychotropic medications in Rwandan patients
Objectives: In Rwanda, no therapeutic monitoring of psychotropic drugs is done. This results in difficult treatment optimisation and exposition to a high risk of toxicity and drug ineffectiveness forExpand
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