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Correlation of intrinsic chemoresistance of non-small-cell lung cancer cell lines with HER-2/neu gene expression but not with ras gene mutations.
- C. Tsai, K. T. Chang, +4 authors A. Gazdar
- Biology, Medicine
- Journal of the National Cancer Institute
- 2 June 1993
BACKGROUND At diagnosis, most small-cell lung cancers (SCLCs) are chemosensitive, whereas non-small-cell lung cancers (NSCLCs) are usually chemoresistant. Activation of ras genes and HER-2/neu genes… Expand
Malignant pleural mesothelioma: Clinicopathology of 16 extrapleural pneumonectomy patients with special reference to early stage features
The earliest pathological events in the development of malignant pleural mesothelioma (MPM) are not understood. The aim of the present study was to elucidate the early histopathological features of… Expand
Diffuse malignant pleural mesothelioma: A multi-institutional clinicopathological study
PurposeThe relative rarity of malignant pleural mesothelioma (MPM) in Japan makes it difficult to perform a large-scale clinicopathological study of this tumor at a single institute. Thus, we… Expand
Association between histological type and neuroendocrine differentiation on drug sensitivity of lung cancer cell lines.
Because most small-cell lung cancers (SCLC) are initially chemosensitive and express neuroendocrine (NE) cell markers and most non-SCLC tumors (NSCLC) are chemoresistant and do not express NE cell… Expand
[A case of "thoracolithiasis"--an unusual isolated calcified lesion in the intrathoracic space].
Correlation of in vitro drug sensitivity testing of long-term small cell lung cancer cell lines with response and survival.
In vitro drug sensitivity testing (DST) of long-term cultures from small cell lung cancer (SCLC) tumours was correlated with response and survival after four cycles of etoposide and cisplatin. 27… Expand
Effects of tumor necrosis factor, alone or in combination with topoisomerase‐ii‐targeted drugs, on human lung cancer cell lines
- G. Giaccone, C. Kadoyama, R. Maneckjee, D. Venzon, R. Alexander, A. Gazdar
- Biology, Medicine
- International journal of cancer
- 15 August 1990
Tumor necrosis factor α (TNF) exhibits cytotoxic activity on some solid tumors and has been reported to be synergistic with topoisomerase‐II‐targeted antineoplastic agents. A wide range of TNF… Expand
[Pulmonary hyalinizing granuloma diagnosed by thoracoscopy].
- C. Kadoyama, T. Yokosuka, M. Otsuji, M. Suzuki
- Nihon Kokyuki Gakkai zasshi = the journal of the…
- 1 June 1999
A 36-year-old woman was examined by our hospital for pulmonary coin shadows in both lungs, as disclosed on chest X-ray films. She had no subjective complaints other than allergic rhinitis, but… Expand
Invasive pulmonary aspergillosis associated with influenza B
Abstract: Invasive pulmonary aspergillosis (IPA) usually occurs in immunocompromised patients. However, rarely, this infection can occur in normal hosts. This review of the literature identified 13… Expand
Intratumoral ethanol injection for malignant tracheobronchial lesions: a new bronchofiberscopic procedure.
We performed intratumoral ethanol injection via a flexible bronchofiberscope in 13 patients with malignant tracheobronchial lesions in order to evaluate its effects on airway dilatation and… Expand