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Circulating gastrointestinal hormone changes in marathon running.
- A. O'Connor, C. Johnston, K. Buchanan, C. Boreham, T. Trinick, C. Riddoch
- International journal of sports medicine
- 1 July 1995
Results show that GI hormone concentrations are affected by marathon running, and there is no direct relationship between the large increases in hormone levels and the occurrence of GI symptoms. Expand
Neuroendocrine tumors. A European view.
- K. Buchanan, C. Johnston, +7 authors T. Kennedy
- The American journal of medicine
- 22 December 1986
Of the non-carcinoid tumors, insulinomas, gastrinomas, and unknown types have the highest incidence, with other types being extremely rare, and the potentially remediable nature of the tumors is stressed, and frequently a good quality of life can be experienced even in the presence of metastatic disease. Expand
NEUROPEPTIDE-F - A NOVEL PARASITIC FLATWORM REGULATORY PEPTIDE FROM MONIEZIA-EXPANSA (CESTODA, CYCLOPHYLLIDEA)
Examination of M. expansa's primary structure shows that it displays significant sequence homology with the vertebrate neuropeptide Y superfamily, suggesting that this platyhelminth-derived peptide is the phylogenetic precursor. Expand
Localization of neuroendocrine tumours with [111In] DTPA-octreotide scintigraphy (Octreoscan): a comparative study with CT and MR imaging.
- W. Shi, C. Johnston, +4 authors E. McIlrath
- QJM : monthly journal of the Association of…
- 1 April 1998
Scintigraphy has a higher sensitivity for tumour detection, and is superior to MR imaging and CT scanning in the identification of previously unsuspected extraliver and lymph node metastases, and may also be helpful for the localization of clinically suspected tumours in patients with MEN-I and ZES. Expand
Neuron-specific enolase as an aid to outcome prediction in head injury.
In nine patients with major head injury, changes in CSF levels reflected changes in serum NSE levels, and in all nine patients, serum N SE decreased to reach normal values, regardless of the outcome as predicted by the GOS. Expand
The frequency of gastrointestinal endocrine tumours in a well-defined population--Northern Ireland 1970-1985.
The reported incidence of gastrointestinal endocrine tumours is variable and it is possible that some tumours are more uncommon than others because of difficulty in diagnosis. Expand
Neuropeptide F (Moniezia expansa): localization and characterization using specific antisera.
- A. Maule, C. Shaw, D. Halton, G. Brennan, C. Johnston, S. Moore
- Biology, Medicine
- 1 December 1992
The C-terminal NPF antiserum has potential for use in the identification and purification of NPF analogues from other platyhelminth parasites. Expand
Oncogene expression in gastroenteropancreatic neuroendocrine tumors
These tumors comprise a functionally and biologically heterogeneous group of neoplasms that rarely show reliable histopathologic signs of malignancy and their exact ontogeny and carcinogenesis remain unknown. Expand
Cell-specific Processing of Chromogranin A in Endocrine Cells of the Rat Stomach
- P. Norlén, W. Curry, +7 authors R. Håkanson
- Biology, Medicine
- The journal of histochemistry and cytochemistry…
- 1 January 2001
It is suggested that each individual endocrine cell type in the rat stomach generates a unique mixture of CgA-derived peptides, probably reflecting cell-specific differences in the post-translational processing of C gA and its peptide products. Expand
Hymenolepis diminuta: intestinal goblet cell response to infection in male C57 mice.
- D. Mckay, D. Halton, M. Mccaigue, C. Johnston, I. Fairweather, C. Shaw
- Biology, Medicine
- Experimental parasitology
- 1 July 1990
Male Wistar rats given a 10-cysticercoid infection and autopsied on Day 0, Day 10, and 15 months p-i showed a statistically significant increase in mucus-containing goblet cells only in the 60-70% region of intestine 10 days p- i; however, the worm burden was not eliminated. Expand