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Clinical and psychometric validation of the EORTC QLQ-CR29 questionnaire module to assess health-related quality of life in patients with colorectal cancer.
This international study aimed to test the measurement properties of the updated European Organisation for Research and Treatment of Cancer (EORTC) questionnaire module for colorectal cancer, the… Expand
Persistent organ failure during the first week as a marker of fatal outcome in acute pancreatitis
Background: In predicted severe acute pancreatitis, many patients develop organ failure and recover without local complications, and mortality is only 14–30%. It has been suggested that half of… Expand
Quality of life in stoma patients
- K. Nugent, P. Daniels, B. Stewart, R. Patankar, C. Johnson
- Diseases of the colon and rectum
- 1 December 1999
BACKGROUND: Patients with stomas face many difficulties both physical and psychological. Little is known about the long-term problems and the impact on patient lifestyle of a permanent stoma. This… Expand
Development of an EORTC disease-specific quality of life module for use in patients with gastric cancer.
Quality of life (QL) is an important outcome in clinical trials in oncology. There is currently no valid international QL measure for gastric cancer. This paper describes the development of a QL… Expand
Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis
BACKGROUND Platelet activating factor (PAF) is believed to amplify the activity of key mediators of the systemic inflammatory response syndrome (SIRS) in acute pancreatitis, resulting in multiorgan… Expand
Symptoms and Quality of Life in Chronic Pancreatitis Assessed by Structured Interview and the EORTC QLQ-C30 and QLQ-PAN26
- D. Fitzsimmons, Stefan Kahl, +6 authors C. Johnson
- The American Journal of Gastroenterology
- 1 April 2005
BACKGROUND AND AIMS:Chronic pancreatitis (CP) produces disabling symptoms and requires major clinical interventions over a number of years. There is consensus that quality-of-life (QoL) assessment… Expand
A prospective audit against national standards of the presentation and management of acute pancreatitis in the South of England
BACKGROUND The incidence of acute pancreatitis shows regional variations in the UK. AIMS To document the incidence and presentation of acute pancreatitis in hospitals in Wessex, and to audit the… Expand
Development of a disease specific quality of life (QoL) questionnaire module to supplement the EORTC core cancer QoL questionnaire, the QLQ-C30 in patients with pancreatic cancer. EORTC Study Group…
There is overwhelming consensus that quality of life assessment is urgently required in pancreatic cancer, yet little research has been conducted. We report on the development of a disease specific… Expand
Stereotactic body radiation therapy with concurrent full-dose gemcitabine for locally advanced pancreatic cancer: a pilot trial demonstrating safety
BackgroundConcurrent chemoradiation is a standard option for locally advanced pancreatic cancer (LAPC). Concurrent conventional radiation with full-dose gemcitabine has significant toxicity.… Expand
General population normative data for the EORTC QLQ-C30 health-related quality of life questionnaire based on 15,386 persons across 13 European countries, Canada and the Unites States.
OBJECTIVE The European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 health-related quality of life questionnaire is one of the most widely used cancer-specific health-related… Expand