• Publications
  • Influence
Visible deformity in childhood leprosy--a 10-year study.
  • B. Kar, C. Job
  • Medicine
  • International journal of leprosy and other…
  • 22 August 2005
Deformity seen in children with leprosy has not often been studied, as the disease itself is less common in children. Deformity, being synonymous with the stigma of leprosy, is a definite socialExpand
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Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy.
Evidence that interferon-gamma may be a physiologic macrophage-activating factor, and that macrophage activation may be defective in lepromatous leprosy, led us to test the effects of intradermalExpand
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Transmission of leprosy: a study of skin and nasal secretions of household contacts of leprosy patients using PCR.
It is generally held that dissemination of Mycobacterium leprae is from nasal mucosa and not through the skin of infected patients. In this study, we evaluated M. leprae in the unbroken skin andExpand
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Tuberculous lymphadenitis in South India--a histopathological and bacteriological study.
Abstract Cultures for mycobacteria and histopathological studies were done on 265 consecutive lymph node biopsies. Of these, 128 nodes showed changes consistent with tuberculosis. Mycobacteria wereExpand
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Seasonal and spatial trends in the detectability of leprosy in wild armadillos.
A survey for leprosy among 565 armadillos from Louisiana and Texas found IgM antibodies to the phenolic glycolipid-1 antigen of Mycobacterium leprae in 16% of the animals. There were no geographicExpand
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The reconstitution of cell-mediated immunity in the cutaneous lesions of lepromatous leprosy by recombinant interleukin 2
Human rIL-2 (10-30 micrograms) was injected intradermally into the skin of patients with lepromatous leprosy with high bacillary loads. All patients responded to the lymphokine with local areas ofExpand
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Transmission of leprosy in nude mice.
Nude mice in groups of 10 were exposed to M. leprae by subcutaneous injection and topically through the nose, lungs, mouth, stomach and skin, broken and unbroken. Animals injected subcutaneously andExpand
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Mechanism of nerve destruction in tuberculoid-borderline leprosy. An electron-microscopic study.
  • C. Job
  • Medicine
  • Journal of the neurological sciences
  • 1 September 1973
Abstract The ultrastructural changes in radial cutaneous nerve biopsies from 3 tuberculoid and 14 tuberculoid-borderline patients were studied. In tuberculoid leprosy the nerve parenchyma was almostExpand
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Role of S-100 staining in differentiating leprosy from other granulomatous diseases of the skin.
Since Mycobacterium leprae are rarely demonstrable in the tuberculoid spectrum of leprosy, a confirmatory diagnosis of leprosy can be made on the basis of finding active destruction of cutaneousExpand
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Segmental necrotizing granulomatous neuritis of leprosy.
In leprosy, the occurrence of necrotizing nodular lesions in peripheral nerves is a relatively uncommon complication. Despite clinical and gross similarities, there are microscopical differencesExpand
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