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Plakoglobin interacts with and increases the protein levels of metastasis suppressor Nm23-H2 and regulates the expression of Nm23-H1

• Zackie Aktary, Kevin Chapman, +7 authors Manijeh Pasdar
• Oncogene
• 2010

Plakoglobin (γ-catenin) is a homolog of β-catenin with similar dual adhesive and signaling functions. The adhesive function of these proteins is mediated by their interactions with cadherins, whereas… (More)

Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition

• C. Ji, B. Yang, +4 authors Z-g Bi
• Oncogene
• 2010

New chemotherapy-enhancing strategies are needed for better cancer therapy. Previous studies suggest that exogenous cell-permeable C6 ceramide may be a useful adjunct to the anti-tumor effects of… (More)

Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin.

• M.. Lecomte, Odette Laneuville, C. Ji, David L Dewitt, W. L. Smith
• The Journal of biological chemistry
• 1994

Aspirin (acetylsalicylate) treatment of human (h) prostaglandin endoperoxide H synthase (PGHS)-1 expressed in cos-1 cells caused a time-dependent inactivation of oxygenase activity. Aspirin treatment… (More)

IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal.

• C. Ji, Karol Kozak, Larry J Marnett
• The Journal of biological chemistry
• 2001

In unstimulated cells, transcription factor NF-kappaB is retained in the cytoplasm by interaction with the inhibitory protein, IkappaBalpha. Appropriate cellular stimuli inactivate IkappaBalpha by… (More)

Geodetic, teleseismic, and strong motion constraints on slip from recent southern Peru subduction zone earthquakes

• Mary E. Pritchard, Edmundo O. Norabuena, +5 authors P. A. Rosen
• 2007

[1] We use seismic and geodetic data both jointly and separately to constrain coseismic slip from the 12 November 1996 Mw 7.7 and 23 June 2001 Mw 8.5 southern Peru subduction zone earthquakes, as… (More)

MiR-146b is a regulator of human visceral preadipocyte proliferation and differentiation and its expression is altered in human obesity

• Ling Chen, Yong-mei Dai, +7 authors Xi-rong Guo
• Molecular and Cellular Endocrinology
• 2014

Visceral obesity is an independent risk factor for metabolic syndrome, and abnormal fat accumulation is linked to increases in the number and size of adipocytes. MiR-146b was a miRNA highly expressed… (More)

TNF-alpha induces mitochondrial dysfunction in 3T3-L1 adipocytes.

• Xiao-hui Chen, Yaping Zhao, +8 authors Xi-rong Guo
• Molecular and cellular endocrinology
• 2010

TNF-alpha was the first proinflammatory cytokine identified linking obesity, insulin resistance and chronic inflammation. However, the mechanism of TNF-alpha in the etiology of insulin resistance is… (More)

Evaluation of the compositional and nutritional values of phytase transgenic corn to conventional corn in roosters.

• Changyue Gao, Q. G. Ma, C. Ji, X. G. Luo, H F Tang, Y. M. Wei
• Poultry science
• 2012

Three experiments were conducted to evaluate the compositional and nutritional values of corn grains [phytase transgenic corn (PTC) and isogenic conventional corn (CC)] and compare the efficacy of… (More)

Activation of the insulin-like growth factor-binding protein-5 promoter in osteoblasts by cooperative E box, CCAAT enhancer-binding protein, and nuclear factor-1 deoxyribonucleic acid-binding…

• C. Ji, Y. Chen, Michael Centrella, Thomas Mccarthy
• Endocrinology
• 1999

Insulin-like growth factor (IGF)-binding protein-5 (IGFBP-5) has IGF-dependent and -independent actions. PGE2 rapidly increases IGFBP-5 expression by osteoblasts through cAMP-dependent processes. A… (More)

C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo

• Q-y Zhu, Zhaoming Wang, +9 authors Yinhui Yang
• Cell Death and Disease
• 2011

Histone deacetylase inhibitors (HDACIs) have shown promising anti-tumor effects for a variety of malignancies, however, many tumors are reportedly resistant to them. In this study, we made a novel… (More)

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