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2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the
Craig T. January, MD, PhD, FACC L. Samuel Wann, MD, MACC, FAHA Joseph S. Alpert, MD, FACC, FAHA Hugh Calkins, MD, FACC, FAHA, FHRS Joseph C. Cleveland Jr., MD, FACC Joaquin E. Cigarroa, MD, FACCExpand
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High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.
  • J. Ma, L. Guo, +6 authors C. January
  • Biology, Medicine
  • American journal of physiology. Heart and…
  • 1 November 2011
Human-induced pluripotent stem cells (hiPSCs) can differentiate into functional cardiomyocytes; however, the electrophysiological properties of hiPSC-derived cardiomyocytes have yet to be fullyExpand
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  • Open Access
Management of patients with atrial fibrillation (compilation of 2006 ACCF/AHA/ESC and 2011 ACCF/AHA/HRS recommendations): a report of the American College of Cardiology/American Heart Association
This document is a compilation of the current American College of Cardiology Foundation/American Heart Association (ACCF/AHA) practice guideline recommendations for atrial fibrillation (AF) from theExpand
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  • Open Access
2011 ACCF/AHA/HRS focused updates incorporated into the ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: a report of the American College of Cardiology
For new or updated text, view the 2011 Focused Update and the 2011 Focused Update on Dabigatran. Text supporting unchanged recommendations has not been updated. It is important that the medicalExpand
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2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the
Jeffrey L. Anderson, MD, FACC, FAHA, Chair Jonathan L. Halperin, MD, FACC, FAHA, Chair-Elect Nancy M. Albert, PhD, RN, FAHA Biykem Bozkurt, MD, PhD, FACC, FAHA Ralph G. Brindis, MD, MPH, MACC Expand
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  • Open Access
Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature.
We have established stably transfected HEK 293 cell lines expressing high levels of functional human ether-a go-go-related gene (HERG) channels. We used these cells to study biochemicalExpand
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Early Afterdepolarizations: Mechanism of Induction and Block A Role for L‐Type Ca2+ Current
Early afterdepolarizations (EADs) are a type of triggered activity found in heart muscle. We used voltage-clamped sheep cardiac Purkinje fibers to examine the mechanism underlying EADs induced nearExpand
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Mechanism of block and identification of the verapamil binding domain to HERG potassium channels.
Calcium channel antagonists have diverse effects on cardiac electrophysiology. We studied the effects of verapamil, diltiazem, and nifedipine on HERG K+ channels that encode IKr in native heartExpand
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  • Open Access
Most LQT2 Mutations Reduce Kv11.1 (hERG) Current by a Class 2 (Trafficking-Deficient) Mechanism
Background— The KCNH2 or human ether-a-go-go related gene (hERG) encodes the Kv11.1 α-subunit of the rapidly activating delayed rectifier K+ current (IKr) in the heart. Type 2 congenital long-QTExpand
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