C. Janich

Publications25
h-index10
Citations242
Highly Influential Citations3
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Screening for Body Dysmorphic Disorder in Dermatological Outpatients
TLDR
The validity of the Dysmorphic Concern Questionnaire (DCQ) as a sensitive and specific screening instrument that can be recommended as a routine assessment instrument in clinical practice is confirmed.
Risperidone-Loaded PLGA–Lipid Particles with Improved Release Kinetics: Manufacturing and Detailed Characterization by Electron Microscopy and Nano-CT
TLDR
The developed lipid-PLGA microparticles are attractive alternatives to pure PLGA-based particles that can be easily tuned by the lipid composition and achieve a nearly zero order release without a lag time over 60 days.
Interaction of DNA with Cationic Lipid Mixtures-Investigation at Langmuir Lipid Monolayers.
Four different binary lipid mixtures composed of a cationic lipid and the zwitterionic colipids DOPE or DPPC, which show different DNA transfer activities in cell culture models, were investigated at…
Lysine-based amino-functionalized lipids for gene transfection: the protonation state in monolayers at the air-liquid interface.
TLDR
Newly synthesized peptide-mimic lysine-based amino-functionalized lipids have been investigated in 2D models as monolayers at the air-liquid interface and it is found that the protonation degree depends linearly on the packing density of the lipid monolayer.
Malonic acid based cationic lipids - The way to highly efficient DNA-carriers.
Overcoming the polycation dilemma - Explorative studies to characterise the efficiency and biocompatibility of newly designed lipofection reagents.
Indomethacin functionalised poly(glycerol adipate) nanospheres as promising candidates for modified drug release
Composites of malonic acid diamides and phospholipids--Impact of lipoplex stability on transfection efficiency.
Composites of malonic acid diamides and phospholipids – Structural parameters for optimal transfection efficiency in A549 cells
TLDR
The lipid mixtures with the fluid cationic lipid OH4 and DOPE have shown comparable transfection efficiency with Lipofectamine 2000® and the huge influence of the helper lipid on the transfections efficiency is demonstrated.
Investigation of Binary Lipid Mixtures of a Three-Chain Cationic Lipid with Phospholipids Suitable for Gene Delivery.
TLDR
Binary lipid mixtures consisting of a three-chain amino-functionalized cationic lipid (DiTT4) with different phospholipids are characterized and efficient lipid compositions were investigated with respect to serum stability.
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