C. J. Sheeba
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Auxin pretreatment promotes regeneration of sugarcane (Saccharum spp. hybrids) midrib segment explants
- G. Franklin, S. Arvinth, C. J. Sheeba, M. Kanchana, N. Subramonian
- Plant Growth Regulation
- 10 November 2006
We have developed a new, simple, quick and genotype-independent method for direct regeneration of sugarcane using novel midrib segment explants. Our protocol involves two steps: the pretreatment of… Expand
Nanoparticles Alter Secondary Metabolism in Plants via ROS Burst
The particles within the size range of 1 and 100 nm are known as nanoparticles (NPs). NP-containing wastes released from household, industrial and medical products are emerging as a new threat to the… Expand
Comprehensive analysis of fibroblast growth factor receptor expression patterns during chick forelimb development.
- C. J. Sheeba, R. Andrade, D. Duprez, I. Palmeirim
- Medicine, Biology
- The International journal of developmental…
- 21 December 2010
Specific interactions between fibroblast growth factors (Fgf1-22) and their tyrosine kinase receptors (FgfR1-4) activate different signalling pathways that are responsible for the biological… Expand
Poly(D,L-lactic-co-glycolic acid) nanoencapsulation reduces Erlotinib-induced subacute toxicity in rat.
- Gregory Marslin, C. J. Sheeba, V. Kalaichelvan, R. Manavalan, P. N. Reddy, G. Franklin
- Materials Science, Medicine
- Journal of biomedical nanotechnology
- 1 October 2009
Erlotinib-HCl is a quinazoline derivative used as a drug in the therapy of non-small-cell lung cancer. The present study was conducted to compare the subacute toxicity induced by Erlotinib-HCl… Expand
Delivery as nanoparticles reduces imatinib mesylate-induced cardiotoxicity and improves anticancer activity
- Gregory Marslin, Ann Mary Revina, +4 authors C. J. Sheeba
- International journal of nanomedicine
- 24 April 2015
Clinical effectiveness of imatinib mesylate in cancer treatment is compromised by its off-target cardiotoxicity. In the present study, we have developed physically stable imatinib mesylate-loaded… Expand
The Roles of T-Box Genes in Vertebrate Limb Development.
Members of the T-box gene family have diverse roles during embryogenesis and many play critical roles in the developing limb. This is exemplified by the fact that, in humans, mutations in T-box genes… Expand
Limb patterning: from signaling gradients to molecular oscillations.
- Caroline J. Sheeba, Raquel P. Andrade, Isabel Palmeirim
- Medicine, Biology
- Journal of molecular biology
- 20 February 2014
The developing forelimb is patterned along the proximal-distal and anterior-posterior axes by opposing gradients of retinoic acid and fibroblast growth factors and by graded sonic hedgehog signaling,… Expand
PEGylated ofloxacin nanoparticles render strong antibacterial activity against many clinically important human pathogens.
- Gregory Marslin, Ann Mary Revina, V. Khandelwal, K. Balakumar, C. J. Sheeba, G. Franklin
- Medicine, Chemistry
- Colloids and surfaces. B, Biointerfaces
- 1 August 2015
The rise of bacterial resistance against important drugs threatens their clinical utility. Fluoroquinones, one of the most important classes of contemporary antibiotics has also reported to suffer… Expand
Test Anxiety Levels of Board Exam Going Students in Tamil Nadu, India
- Revina Ann Mary, Gregory Marslin, G. Franklin, C. J. Sheeba
- BioMed research international
- 21 July 2014
The latest report by the National Crime Records Bureau has positioned Tamil Nadu as the Indian state with highest suicide rate. At least in part, this is happening due to exam pressure among… Expand
Getting a handle on embryo limb development: Molecular interactions driving limb outgrowth and patterning.
Development of the vertebrate embryo involves multiple segmentation processes to generate a functional, articulated organism. Cell proliferation, differentiation and patterning involve spatially and… Expand