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- Publications
- Influence
Ligand binding to the serotonin transporter: equilibria, kinetics, and ion dependence.
- C. J. Humphreys, S. C. Wall, G. Rudnick
- Chemistry, Medicine
- Biochemistry
- 9 August 1994
The effects of Na+ and Cl- on the binding of [3H]imipramine and the cocaine analog [125I]-beta-carbomethoxy-3 beta-(4-iodophenyl)tropane([125I]-beta-CIT) to the human platelet serotonin transporter… Expand
Chemical mapping and formation of V-defects in InGaN multiple quantum wells
- Nikhil Sharma, P. Thomas, D. Tricker, C. J. Humphreys
- Physics
- 22 August 2000
InGaN multiple-quantum-well structures grown by metal–organic chemical-vapor deposition on GaN and capped by p-type GaN are found to contain inverted pyramids of indium-free GaN. High-resolution… Expand
Antidepressant binding to the porcine and human platelet serotonin transporters.
- C. J. Humphreys, J. Levin, G. Rudnick
- Chemistry, Medicine
- Molecular pharmacology
- 1 June 1988
The ability of four antidepressant drugs, imipramine, alaproclate, norzimelidine, and fluvoxamine, to inhibit serotonin transport into platelet plasma membrane vesicles was tested over a range of… Expand
Platelet serotonin transporter.
- G. Rudnick, C. J. Humphreys
- Chemistry, Medicine
- Methods in enzymology
- 1992
Substrate and inhibitor binding and translocation by the platelet plasma membrane serotonin transporter.
- C. J. Humphreys, D. Beidler, G. Rudnick
- Chemistry, Medicine
- Biochemical Society transactions
- 1 February 1991
The Na+ and Cl- dependence of imipramine binding and dissociation were determined in platelet plasma membrane vesicles. Equilibrium imipramine binding affinity depends on Na+ binding to two… Expand
Effects of electron-beam exposure on a ruthenium nanocluster polymer
- M. R. Thomas, H. Ahmed, +5 authors C. J. Humphreys
- Chemistry
- 29 June 2001
The properties of the ruthenium nanocluster polymer of formula [Ru6C(CO)15P(C6H5)2CCP(C6H5)2]n are studied by atomic-force microscopy, Fourier-transform infrared spectroscopy, and electron microscopy… Expand
Variation of dislocation morphology with strain in Ge x Si 1 - x epilayers on (100)Si
- E. P. Kvam, D. Maher, C. J. Humphreys
- Materials Science
- 1 September 1990
A change in microstructure, including dislocation Burgers vector, length, and behavior, has been observed to occur when the epilayer mismatch is varied in Ge x Si 1− x layers grown on (100) Si. At… Expand
Serotonin Transport by Platelet Plasma and Granule Membranes
- G. Rudnick, C. J. Humphreys, G. Dean
- Chemistry, Medicine
- Annals of the New York Academy of Sciences
- 1 November 1985
2-Iodoimipramine, a novel ligand for the serotonin transporter.
- C. J. Humphreys, D. Cassel, G. Rudnick
- Chemistry, Medicine
- Molecular pharmacology
- 1 October 1989
Iodoimipramine was synthesized by iodinating imipramine with ICI. Iodoimipramine competitively inhibits [3H]imipramine binding with a KI of 0.52 nM and also inhibits [3H]serotonin transport… Expand
Silica‐Supported Fe ? Pd Bimetallic Particles: Formation from Mixed‐Metal Clusters and Catalytic Activity
- P. Braunstein, R. Devenish, +5 authors Michel Ries
- Chemistry
- 1 July 1988