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- Publications
- Influence
Synthesis, Gastroprotective, Antisecretory and Anti‐helicobacter Effect of N‐[3‐(3‐(1‐Piperidinylmethyl) phenoxy)propyl]‐hydroxyacetamide 2‐Hydroxypropane‐1,2,3‐tricarboxylate Bismuth (3+) Complex…
- C. Ivanov, O. Petkov, +7 authors E. Savov
- Chemistry, Medicine
- The Journal of pharmacy and pharmacology
- 1 March 1996
MX, (N‐[3‐(3‐(1‐piperidinylmethyl)phenoxy)propyl]‐hydroxyacetamide 2‐hydroxypropane‐1,2,3‐tricar‐boxylate bismuth (3+) complex) is a novel salt of the active metabolite of H2‐antagonist roxatidine… Expand
Effects of 4-(4-bromophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride on acute gastric lesions, acid secretion in rats and on some hemodynamic parameters in cats.
- R. Atanassova, O. Petkov, C. Ivanov, N. Valchanova, M. Bozhikov
- Medicine
- Methods and findings in experimental and clinical…
- 1999
The effectiveness of 4-(4-bromophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (AN12) on acute ulcer models and gastric acid secretion in rats was compared with the action of the… Expand
Effect of roxatidine bismuth citrate (MX1) against acetylsalicylic acid- and indomethacin-induced gastric mucosal damage in rats.
- K. Marazova, E. Klouchek, +5 authors K. Hotta
- Medicine, Chemistry
- Methods and findings in experimental and clinical…
- 1 October 1998
We have studied the effect of the newly synthesized agent, roxatidine bismuth citrate (N-[3-(3-(1-piperidinyl-methyl)phenoxy)propyl]-hydroxyacetamide-2-… Expand
EFFECTS OF A NEWLY SYNTHESIZED HISTAMINE H2-RECEPTOR ANTAGONIST ON THE HISTAMINE-INDUCED CHANGES IN PH AND GASTRIC ACID SECRETION IN ANAESTHETIZED RAT S
- G. Spassov, E. Sotirov, G. Dobreva, C. Ivanov, S. Todorov
- Chemistry
- 1997
Effects of compound IS-35 on intraocular pressure.
- M. Markov, C. Ivanov, P. Uzunov, R. Ovcharov
- Medicine
- Methods and findings in experimental and clinical…
- 1 July 1988
The influence of compound IS-35 on intraocular pressure of unanesthetized rabbits was studied. In some cases intraocular pressure was measured with either the tonometer of Schiotz and was calculated… Expand
High-performance liquid chromatographic separation of intermediate products and potential impurities by the synthesis of roxatidin
Abstract A high-performance liquid chromatographic method is described for routine analytical control of the synthesis of roxatidin —a new β-blocker. Under control are three groups of compounds:… Expand