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Synthesis, Gastroprotective, Antisecretory and Anti‐helicobacter Effect of N‐[3‐(3‐(1‐Piperidinylmethyl) phenoxy)propyl]‐hydroxyacetamide 2‐Hydroxypropane‐1,2,3‐tricarboxylate Bismuth (3+) Complex
MX, (N‐[3‐(3‐(1‐piperidinylmethyl)phenoxy)propyl]‐hydroxyacetamide 2‐hydroxypropane‐1,2,3‐tricar‐boxylate bismuth (3+) complex) is a novel salt of the active metabolite of H2‐antagonist roxatidineExpand
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Effects of 4-(4-bromophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride on acute gastric lesions, acid secretion in rats and on some hemodynamic parameters in cats.
The effectiveness of 4-(4-bromophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (AN12) on acute ulcer models and gastric acid secretion in rats was compared with the action of theExpand
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Effect of roxatidine bismuth citrate (MX1) against acetylsalicylic acid- and indomethacin-induced gastric mucosal damage in rats.
We have studied the effect of the newly synthesized agent, roxatidine bismuth citrate (N-[3-(3-(1-piperidinyl-methyl)phenoxy)propyl]-hydroxyacetamide-2-Expand
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Effects of compound IS-35 on intraocular pressure.
The influence of compound IS-35 on intraocular pressure of unanesthetized rabbits was studied. In some cases intraocular pressure was measured with either the tonometer of Schiotz and was calculatedExpand
High-performance liquid chromatographic separation of intermediate products and potential impurities by the synthesis of roxatidin
Abstract A high-performance liquid chromatographic method is described for routine analytical control of the synthesis of roxatidin —a new β-blocker. Under control are three groups of compounds:Expand
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