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Epicardial FSTL1 reconstitution regenerates the adult mammalian heart
The elucidation of factors that activate the regeneration of the adult mammalian heart is of major scientific and therapeutic importance. Here we found that epicardial cells contain a potentExpand
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APJ ACTS AS A DUAL RECEPTOR IN CARDIAC HYPERTROPHY
Cardiac hypertrophy is initiated as an adaptive response to sustained overload but progresses pathologically as heart failure ensues. Here we report that genetic loss of APJ, a G-protein-coupledExpand
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Proceso de admisión al Residentado Médico en el Perú: Características, preferencias y propuestas de los médicos que se preparan para rendir el examen de admisión 2011
Resumen es: Objetivo: Describir las caracteristicas, preferencias y propuestas de los medicos que se preparan para rendir el examen, respecto al proceso de admision ...
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Effect of geraniol on rat cardiomyocytes and its potential use as a cardioprotective natural compound
Aims: Reactive oxygen species (ROS) are generated in the ischaemic myocardium especially during early reperfusion and affect myocardial function and viability. Monoterpenes have been proposed to playExpand
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b-Annulated 1,4-dihydropyridines as Notch inhibitors.
The Notch signaling pathway is involved in cell proliferation and differentiation, and has been recognized as an active pathway in regenerating tissue and cancerous cells. Notch signaling inhibitionExpand
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Peptidomimetic Polo‐Box‐Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor
The polo‐box domain (PBD) of PLK1 determines mitotic substrate recognition and subcellular localization. Compounds that target PLK1 selectively are required due to the tumor‐suppressor roles of PLK3.Expand
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Self-regulation of embryonic pattern in Xenopus embryos
Presidential symposium Program/Abstract # 1 Self-regulation of embryonic pattern in Xenopus embryos Eddy De Robertis, Lucho Fuentealba, Edward Eivers, Cecilia Hurtado, Andrea Ambrosio, VincentExpand
Admission competition for medical residency in Peru: characteristics, preferences, and proposals from physicians who are preparing for taking the national medical residency examination in 2011.
Objetivo: Describir las características, preferencias y propuestas de los médicos que se preparan para rendir el examen, respecto al proceso de admisión vigente al residentado médico en el Perú.Expand
Prediction of revascularization by coronary CT angiography using a machine learning ischemia risk score
The machine learning ischemia risk score (ML-IRS) is a machine learning–based algorithm designed to identify hemodynamically significant coronary disease using quantitative coronary computedExpand