• Publications
  • Influence
Cardiovascular complications.
TLDR
The Task Force recommends encouragement of use of diabetic nonhuman primates for cardiovascular research and institution of measures to increase their supply and availability by expanding current colonies, screening newly imported animals for diabetes, and establishing a visiting scientist's program allowing investigators to study diabetic primates at resource centers. Expand
Obesity in free-ranging rhesus macaques.
Spontaneous obesity in free-ranging rhesus macaques (Macaca mulatta) was assessed in terms of body size, body fat distribution, endocrinological/metabolic indices, and social and familial factors.Expand
Metabolism of myo-inositol in animals. II. Complete catabolism of myo-inositol-14C by rat kidney slices.
TLDR
The results of earlier tracer experiments suggest that the kidney is the only organ of importance in inositol catabolism, and the data indicate that a rat's kidneys can catabolize all of the inositols ingested in an average daily diet. Expand
Basement Membrane Thickness in Muscle Capillaries of Normal and Spontaneously Diabetic Macaca Nigra
  • C. Howard
  • Chemistry, Medicine
  • Diabetes
  • 1 February 1975
TLDR
Thickness correlated significantly with the degree and severity of diabetes; greater thickness was associated with decreased glucose tolerance, decreased serum insulin, and increased glucose and triglyceride. Expand
Longitudinal studies on the development of diabetes in individual Macaca nigra
  • C. Howard
  • Biology, Medicine
  • Diabetologia
  • 1 May 1986
TLDR
The lesion precedes development of overt diabetes in Macaca nigra, in which there was gradual loss of islet secretory cells and concurrent amyloid deposition. Expand
Insular Amyloidosis in Spontaneously Diabetic Nonhuman Primates
TLDR
Results indicate that nonhuman primates offer a model for studying the sequential development of insular amyloidotic diabetes mellitus. Expand
Spontaneous diabetes mellitus in Macaca cyclopis and Mandrillus leucophaeus: case reports.
TLDR
Spontaneous diabetes mellitus was reported in a Mandrillus leucophaeus (drill baboon) and a Mpacaca cyclopis and both monkeys had extensive amyloid infiltration into the islets of Langerhans and loss of beta cells. Expand
The effect of glycerol 3-phosphate on fatty acid synthesis.
TLDR
Observations suggest that the microsomal stimulation of fatty acid synthesis may be caused at least in part by transfer of acyl groups from long chain fatty acyl coenzyme A to glycerol 3-phosphate. Expand
Lipogenesis from glucose-2- 14 C and acetate-1- 14 C in aorta.
  • C. Howard
  • Biology, Medicine
  • Journal of lipid research
  • 1 November 1971
TLDR
Fatty acid synthesis was similar from both acetate-1-(14)C and the 2 carbon unit derived from glucose-2-( 14)C, viz., predominantly de novo synthesis of fatty acids with 14 and 16 carbon atoms, and elongation for those of 18 carbons and longer. Expand
Hydrolysis of cholesteryl linoleate by a high-speed supernatant preparation of rat and monkey aorta.
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