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  • Influence
Investigation of a unilateral pleural effusion in adults: British Thoracic Society pleural disease guideline 2010
Pleural effusions are a common medical problem with more than 50 recognised causes including disease local to the pleura or underlying lung, systemic conditions, organ dysfunction and drugs.1 Expand
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Predicting survival in malignant pleural effusion: development and validation of the LENT prognostic score
Background Malignant pleural effusion (MPE) causes debilitating breathlessness and predicting survival is challenging. This study aimed to obtain contemporary data on survival by underlying tumourExpand
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Evaluating the efficacy of thoracoscopy and talc poudrage versus pleurodesis using talc slurry (TAPPS trial): protocol of an open-label randomised controlled trial
Introduction The management of recurrent malignant pleural effusions (MPE) can be challenging. Various options are available, with the most efficacious and widely used being talc pleurodesis. TalcExpand
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Testing mapping algorithms of the cancer-specific EORTC QLQ-C30 onto EQ-5D in malignant mesothelioma
BackgroundIn order to estimate utilities for cancer studies where the EQ-5D was not used, the EORTC QLQ-C30 can be used to estimate EQ-5D using existing mapping algorithms. Several mapping algorithmsExpand
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Observing social machines part 1: what to observe?
We argue for observation of multiple interacting machines throughout their lifecycle, and further suggest that the diversity and polymorphous aspects of Social Machines require mixed observation methodologies in order to capture their driving forces. Expand
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Outpatient Talc Administration by Indwelling Pleural Catheter for Malignant Effusion
BACKGROUND Malignant pleural effusion affects more than 750,000 persons each year across Europe and the United States. Pleurodesis with the administration of talc in hospitalized patients is the mostExpand
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The Role of CT Pulmonary Angiography in the Investigation of Unilateral Pleural Effusions
Background: Pulmonary embolism (PE) is frequently cited as a common primary cause of unilateral pleural effusion, but in clinical practice appears to be uncommon. Objectives: In order to evaluateExpand
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The effect of chemotherapy on health-related quality of life in mesothelioma: results from the SWAMP trial
Background:The effect of chemotherapy on health-related quality of life (HRQoL) in malignant pleural mesothelioma (MPM) is poorly understood. Patient-individualised prognostication and prediction ofExpand
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Setting up a specialist pleural disease service
The past decade has seen a dramatic rise in clinical and research interests in pleural disease in parallel with rising incidences of pleural cancers and infection worldwide. Development of specialistExpand
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