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Behavioural and biochemical responses of two marine invertebrates Scrobicularia plana and Hediste diversicolor to copper oxide nanoparticles.
TLDR
No obvious neurotoxicity effects were revealed since in both species, no changes in cholinesterasic activity occurred in response to both forms of Cu exposure and ecotoxicity effects seem to be related to CuO NPs themselves. Expand
Complex Toxin Profile of French Mediterranean Ostreopsis cf. ovata Strains, Seafood Accumulation and Ovatoxins Prepurification
TLDR
Toxin extracts obtained from collected biomass were purified using different techniques such as liquid-liquid partition or size exclusion, and open-column chromatography with Sephadex LH20 phase yielded the best results with a cleanup efficiency of 93% and recovery of about 85%, representing an increase of toxin percentage by 13 fold. Expand
Antiparasitic activity of some New Caledonian medicinal plants.
TLDR
Among the selected plants, Scaevola balansae and Premna serratifolia L. were the most active against Leishmania donovani with IC(50) values between 5 and 10microg/ml. Expand
Dioxin-like, non-dioxin like PCB and PCDD/F contamination in European eel (Anguilla anguilla) from the Loire estuarine continuum: spatial and biological variabilities.
TLDR
Overall, the contamination level in the eels from this estuary was shown to be low for PCDD/Fs and intermediate for dl and ndl-PCBs, compared to other international/national areas. Expand
Synthesis and anticonvulsant and neurotoxic properties of substituted N-phenyl derivatives of the phthalimide pharmacophore.
TLDR
Electrophysiology studies on compound 17 point out its ability to potentiate GABA-evoked current responses with a failure to directly activate the GABAA receptor and to affect, at 100 microM excitatory nonNMDA, but not NMDA, receptors with a 25% block of kainate-evoking response. Expand
Azaspiracid accumulation, detoxification and biotransformation in blue mussels (Mytilus edulis) experimentally fed Azadinium spinosum.
TLDR
Kinetics of accumulation, detoxification and biotransformation were evaluated, as well as the toxin distribution and the effect of A. spinosum on mussel digestive gland tubules. Expand
Extended evaluation of polymeric and lipophilic sorbents for passive sampling of marine toxins.
TLDR
This study has significantly extended the range of sorbents for passive sampling of marine toxins, and for the first time demonstrated the usefulness of the polymeric Oasis HLB and Strata-X sorbent materials in laboratory and field studies for various microalgal toxins. Expand
Toxicity screening of 13 Gambierdiscus strains using neuro-2a and erythrocyte lysis bioassays.
TLDR
It is confirmed that at least one species from the Atlantic Ocean demonstrates similar toxicity as the most toxic strains from the Pacific, even if the metabolites in fish have so far been shown to be more toxic in the Pacific Ocean. Expand
Characterization of ovatoxin-h, a new ovatoxin analog, and evaluation of chromatographic columns for ovatoxin analysis and purification.
TLDR
Investigation of a French O. ovata strain collected at Villefranche-sur-Mer during a bloom in 2011 confirmed the production of ovatoxins-a to -e and revealed the presence of a new ovat toxin analog, named ovatoxin-h, which is situated between C42 and C49. Expand
Dissolved azaspiracids are absorbed and metabolized by blue mussels (Mytilus edulis).
TLDR
Mussels (whole flesh) accumulated AZAs to levels above the regulatory limit, except at the lower levels of dissolved AZAs, and the toxin profile of the mussels varied significantly with treatment. Expand
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