C. Hennekens

Publications989
h-index197
Citations169,484
Highly Influential Citations4,044
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Reproducibility and validity of a semiquantitative food frequency questionnaire.
TLDR
Data indicate that a simple self-administered dietary questionnaire can provide useful information about individual nutrient intakes over a one-year period.
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C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women.
TLDR
The addition of the measurement of C-reactive protein to screening based on lipid levels may provide an improved method of identifying persons at risk for cardiovascular events.
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Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men.
TLDR
The reduction associated with the use of aspirin in the risk of a first myocardial infarction appears to be directly related to the level of C-reactive protein, raising the possibility that antiinflammatory agents may have clinical benefits in preventing cardiovascular disease.
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Epidemiology in Medicine
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Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men.
TLDR
A role for cytokine-mediated inflammation in the early stages of atherogenesis is supported in apparently healthy men, and elevated levels of IL-6 are associated with increased risk of future MI.
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A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women.
TLDR
These epidemiologic data suggest that a high dietary glycemic load from refined carbohydrates increases the risk of CHD, independent of known coronary disease risk factors.
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Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease.
TLDR
In this trial among healthy men, 12 years of supplementation with beta carotene produced neither benefit nor harm in terms of the incidence of malignant neoplasms, cardiovascular disease, or death from all causes.
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Low-density lipoprotein subclass patterns and risk of myocardial infarction.
TLDR
The association of low-density lipoprotein (LDL) subclass patterns with coronary heart disease was investigated in a case-control study of nonfatal myocardial infarction and multivariate logistic regression analyses showed that both high-density cholesterol and triglyceride levels contributed to the risk associated with the small, dense LDL subclass pattern.
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Cholesteryl Ester Transfer Protein: A Novel Target for Raising HDL and Inhibiting Atherosclerosis
TLDR
Small-molecule inhibitors of CETP have now been tested in human subjects and shown to increase the concentration of HDL cholesterol while decreasing that of LDL cholesterol and apoB, and test the hypothesis in randomized trials of humans that pharmacological inhibition of CETp retards the development of atherosclerosis.
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A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians.
OBJECTIVE To assess prospectively the risk of coronary heart disease associated with elevated plasma levels of homocyst(e)ine. DESIGN Nested case-control study using prospectively collected blood…
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