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Anticoagulation Control and Prediction of Adverse Events in Patients With Atrial Fibrillation: A Systematic Review
In atrial fibrillation patients receiving orally administered anticoagulation treatment, TTR and percentage of INRs in range effectively predict INR control and data from retrospective studies support the use of TTR to accurately predict reductions in adverse events.
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children.
The effects of oseltamivir on time to first alleviation of symptoms and hospitalisations using the intention-to-treat (ITT) population and tested five hypotheses generated post-protocol publication are reviewed.
Home measurement of blood pressure and cardiovascular disease: systematic review and meta-analysis of prospective studies
Home BP remained a significant predictor of cardiovascular mortality and cardiovascular events after adjusting for office BP suggesting it is an important prognostic variable over and above that of office BP.
A systematic review and meta-analysis: probiotics in the treatment of irritable bowel syndrome
Probiotics may have a role in alleviating some of the symptoms of IBS, a condition for which currently evidence of efficacy of drug therapies is weak, however, as IBS is a condition that is chronic and usually intermittent longer term trials are recommended.
Relative effectiveness of clinic and home blood pressure monitoring compared with ambulatory blood pressure monitoring in diagnosis of hypertension: systematic review
Neither clinic nor home measurement had sufficient sensitivity or specificity to be recommended as a single diagnostic test, if ambulatory monitoring is taken as the reference standard, then treatment decisions based on clinic or home blood pressure alone might result in substantial overdiagnosis.
Post-marketing withdrawal of 462 medicinal products because of adverse drug reactions: a systematic review of the world literature
There are discrepancies in the patterns of withdrawal of medicinal products from the market when adverse reactions are suspected, and withdrawals are inconsistent across countries.