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A chemosensory system that regulates biofilm formation through modulation of cyclic diguanylate levels.
- Jason W. Hickman, Delia F. Tifrea, C. Harwood
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 4 October 2005
Pseudomonas aeruginosa causes chronic biofilm infections, and its ability to attach to surfaces and other cells is important for biofilm formation and maintenance. Mutations in a gene called wspF,… Expand
THE β-KETOADIPATE PATHWAY AND THE BIOLOGY OF SELF-IDENTITY
▪ Abstract The β-ketoadipate pathway is a chromosomally encoded convergent pathway for aromatic compound degradation that is widely distributed in soil bacteria and fungi. One branch converts… Expand
Identification of FleQ from Pseudomonas aeruginosa as a c‐di‐GMP‐responsive transcription factor
High levels of the intracellular signalling molecule cyclic diguanylate (c‐di‐GMP) supress motility and activate exopolysaccharide (EPS) production in a variety of bacterial species. In many bacteria… Expand
Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris
Rhodopseudomonas palustris is among the most metabolically versatile bacteria known. It uses light, inorganic compounds, or organic compounds, for energy. It acquires carbon from many types of green… Expand
The Pseudomonas aeruginosa RpoS regulon and its relationship to quorum sensing
- M. Schuster, Andrew C. Hawkins, C. Harwood, E. P. Greenberg
- Biology, Medicine
- Molecular microbiology
- 1 February 2004
In Escherichia coli and some other γ‐Proteobacteria, the alternative σ factor RpoS functions as a regulator of the general stress response. The role of RpoS in Pseudomonas aeruginosa is not clear.… Expand
The beta-ketoadipate pathway and the biology of self-identity.
The beta-ketoadipate pathway is a chromosomally encoded convergent pathway for aromatic compound degradation that is widely distributed in soil bacteria and fungi. One branch converts… Expand
Anaerobic metabolism of aromatic compounds via the benzoyl-CoA pathway
Aromatic compounds are important growth substrates for microorganisms. They form a large group of diverse compounds including lignin monomers, amino acids, quinones, and flavonoids. Aerobic aromatic… Expand
Responses of Pseudomonas aeruginosa to low oxygen indicate that growth in the cystic fibrosis lung is by aerobic respiration
Pseudomonas aeruginosa in the lungs of cystic fibrosis patients grows to high densities in mucopurulent material that is depleted in oxygen. Some have concluded that growth in these circumstances is… Expand
PcaK, a high-affinity permease for the aromatic compounds 4-hydroxybenzoate and protocatechuate from Pseudomonas putida.
PcaK is a transporter and chemoreceptor protein from Pseudomonas putida that is encoded as part of the beta-ketoadipate pathway regulon for aromatic acid degradation. When expressed in Escherichia… Expand
Carbon dioxide fixation as a central redox cofactor recycling mechanism in bacteria
The Calvin-Benson-Bassham cycle (Calvin cycle) catalyzes virtually all primary productivity on Earth and is the major sink for atmospheric CO2. A less appreciated function of CO2 fixation is as an… Expand