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Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine.
BACKGROUND Acute rejection is a serious and frequent complication of renal transplantation, and its diagnosis is contingent on the invasive procedure of allograft biopsy. A noninvasive diagnosticExpand
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Messenger RNA for FOXP3 in the urine of renal-allograft recipients.
BACKGROUND The outcome of renal transplantation after an episode of acute rejection is difficult to predict, even with an allograft biopsy. METHODS We studied urine specimens from 36 subjects withExpand
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Outcome of Kidney Transplantation Using Expanded Criteria Donors and Donation After Cardiac Death Kidneys: Realities and Costs
  • R. Saidi, N. Elias, +11 authors D. Ko
  • Medicine
  • American journal of transplantation : official…
  • 1 December 2007
Expanded criteria donors (ECDs) and donation after cardiac death (DCD) provide more kidneys in the donor pool. However, the financial impact and the long‐term benefits of these kidneys have beenExpand
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Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine.
BACKGROUND We explored the hypothesis that measurements of mRNA encoding interferon-inducible protein-10 (IP-10) or the chemokine receptor CXCR3 in urinary cells offer a noninvasive means ofExpand
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Independent Risk Factors for Urinary Tract Infection and for Subsequent Bacteremia or Acute Cellular Rejection: A Single-Center Report of 1166 Kidney Allograft Recipients
Background Urinary tract infection (UTI) is a frequent, serious complication in kidney allograft recipients. Methods We reviewed the records of 1166 kidney allograft recipients who received theirExpand
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Alginate Encapsulant Incorporating CXCL12 Supports Long‐Term Allo‐ and Xenoislet Transplantation Without Systemic Immune Suppression
Islet transplantation represents a potentially curative approach for individuals with Type I Diabetes. The requirement for systemic immune suppression to control immune‐mediated rejection ofExpand
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Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts
Background. Serine proteinase inhibitor (PI)-9 with a reactive center P1 (Glu)-P1′ is a natural antagonist of granzyme B and is expressed in high levels in cytotoxic T lymphocytes (CTL). In view ofExpand
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The role of air plethysmography in monitoring results of venous surgery.
The development of an objective, noninvasive method to assess the hemodynamic effects of venous surgery has long been awaited. Previous methods used to evaluate the results of surgery for varicoseExpand
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Concurrent Acute Cellular Rejection Is an Independent Risk Factor for Renal Allograft Failure in Patients With C4d-Positive Antibody-Mediated Rejection
Background Identification of risk factors for renal allograft failure after an episode of acute antibody-mediated rejection (AMR) may help the outcome of this difficult-to-treat complication. MethodsExpand
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CD103 mRNA levels in urinary cells predict acute rejection of renal allografts1
Background. CD103 is displayed on the cell surface of alloreactive CD8 cytotoxic T lymphocytes (CTLs) and is a critical component for the intraepithelial homing of T cells. Because intratubularExpand
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