Author pages are created from data sourced from our academic publisher partnerships and public sources.
Substituent constants for correlation analysis in chemistry and biology
Bring home now the book enPDFd substituent constants for correlation analysis in chemistry and biology to be your sources when going to read. It can be your new collection to not only display in your… Expand
Partition coefficients and their uses
Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity.
- A. Debnath, R. L. Lopez de Compadre, G. Debnath, A. Shusterman, C. Hansch
- Chemistry, Medicine
- Journal of medicinal chemistry
- 1 February 1991
A review of the literature yielded data on over 200 aromatic and heteroaromatic nitro compounds tested for mutagenicity in the Ames test using S. typhimurium TA98. From the data, a quantitative… Expand
Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs.
Matrix metalloproteinases (MMPs) are a large family of calcium-dependent zinc-containing endopeptidases, which are responsible for the tissue remodeling and degradation of the extracellular matrix… Expand
A survey of Hammett substituent constants and resonance and field parameters
The Hammett equation (and its extended forms) has been one of the most widely used means for the study and interpretation of organic reactions and their mechanisms. Although the Hammett methodology… Expand
p-σ-π Analysis. A Method for the Correlation of Biological Activity and Chemical Structure
The relative toxicity of compounds in mainstream cigarette smoke condensate.
Many different in vivo and in vitro tests are currently used to assess the toxicity of chemicals and complex mixtures such as cigarette smoke condensate. In vivo tests include assays in rodents to… Expand
Quantitative approach to biochemical structure-activity relationships
- C. Hansch
- 1 August 1969
Hydrophobicity and central nervous system agents: on the principle of minimal hydrophobicity in drug design.
- C. Hansch, J. Björkroth, A. Leo
- Chemistry, Medicine
- Journal of pharmaceutical sciences
- 1 September 1987
The problem of getting drugs across the so-called blood-brain barrier (BBB) has long been under extensive investigation; however, the other side of the problem, that of keeping drugs out of the… Expand