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Analysis of CD14 expression levels in putative mesenchymal progenitor cells isolated from equine bone marrow.
A long-term goal of mesenchymal progenitor cell (MPC) research is to identify cell-surface markers to facilitate MPC isolation. One reported MPC feature in humans and other species is lack of CD14Expand
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The Effects of Platelet-Rich Plasma on Cartilage: Basic Science and Clinical Application
Platelet-rich plasma (PRP) is emerging as a biological therapy for the treatment of cartilage injuries and for intra-articular application to address knee pain. Basic science studies indicate thatExpand
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Comparison of gene-specific DNA methylation patterns in equine induced pluripotent stem cell lines with cells derived from equine adult and fetal tissues.
Cellular pluripotency is associated with expression of the homeobox transcription factor genes NANOG, SOX2, and POU5F1 (OCT3/4 protein). Some reports suggest that mesenchymal progenitor cells (MPCs)Expand
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Embryonic stem cells and iPS cells: sources and characteristics.
The field of regenerative medicine research is rapidly expanding. One area of interest to equine researchers is the possibility of isolating or generating pluripotent cells, capable of producingExpand
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Assessing the function of mesenchymal stromal cells: all that glitters is not gold.
Although the use of mesenchymal stromal cells (MSCs) is growing in both small and large animals for the treatment of conditions such as tendonitis and joint disease, our understanding of theirExpand
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Embryonic S tem C ells and i PS C ells: S ources and C haracteristics
By definition, embryonic stem (ES) cells are pluripotent, meaning they can form tissues from all 3 primary germ layers (ectoderm, endoderm, and mesoderm) of the embryo. This differs from totipotencyExpand