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Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging.
New neurons are generated in the adult hippocampus throughout life by neural stem/progenitor cells (NSCs), and neurogenesis is a plastic process responsive to external stimuli. We show that canonicalExpand
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Wood thrush postfledging movements and habitat use in Northern Virginia
We monitored 42 radio-tagged, fledgling Wood Thrushes (Hylocichla mustelina) to investigate movement and habitat use during the postfledging period. Fledglings' mean (± SE) age at dispersal from theExpand
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Conservation of Grassland Birds in North America: Understanding Ecological Processes in Different Regions: "Report of the AOU Committee on Conservation"
—Many species of birds that depend on grassland or savanna habitats have shown substantial overall population declines in North America. To understand the causes of these declines, we examined theExpand
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Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment
Gene therapy in the central nervous system (CNS) is hindered by the presence of the blood–brain barrier, which restricts access of serum constituents and peripheral cells to the brain parenchyma.Expand
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Reelin Deficiency and Displacement of Mature Neurons, But Not Neurogenesis, Underlie the Formation of Granule Cell Dispersion in the Epileptic Hippocampus
Mesio-temporal lobe epilepsy (MTLE) is often accompanied by granule cell dispersion (GCD), a widening of the granule cell layer. The molecular determinants of GCD are poorly understood. Here, we usedExpand
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Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus
Metabotropic GABAB receptors mediate slow inhibitory effects presynaptically and postsynaptically. Using preembedding immunohistochemical methods combined with quantitative analysis of GABAB receptorExpand
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Effects of prior nesting success on site fidelity and breeding dispersal : An experimental approach
-Based on more than 300 individually marked American Robins (Turdus migratorius) and Brown Thrashers (Toxostoma rufum), I tested three hypotheses to explain low return rates of birds whose nestingExpand
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Effects of seven silvicultural treatments on terrestrial salamanders
We compared the relative abundance of terrestrial salamanders before and after application of seven regeneration treatments in a low-elevation, southern Appalachian hardwood forest in southwestExpand
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Role for Reelin in the Development of Granule Cell Dispersion in Temporal Lobe Epilepsy
The reelin signaling pathway plays a crucial role during the development of laminated structures in the mammalian brain. Reelin, which is synthesized and secreted by Cajal–Retzius cells in theExpand
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Mutations of CASK cause an X-linked brain malformation phenotype with microcephaly and hypoplasia of the brainstem and cerebellum.
CASK is a multi-domain scaffolding protein that interacts with the transcription factor TBR1 and regulates expression of genes involved in cortical development such as RELN. Here we describe aExpand
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