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Long‐term effect of interferon alpha‐2b plus ribavirin therapy on incidence of hepatocellular carcinoma in patients with hepatitis C virus‐related cirrhosis
Summary.  We assessed the efficacy of interferon (IFN) alpha‐2b plus ribavirin therapy in patients with hepatitis C virus (HCV)‐related cirrhosis, and elucidated the risk factors for the developmentExpand
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Prognostic significance of p62/SQSTM1 subcellular localization and LC3B in oral squamous cell carcinoma
Background:Autophagy is a programmed cell survival mechanism that has a key role in both physiologic and pathologic conditions. The relationship between autophagy and cancer is complex becauseExpand
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Mutations in the NS5A and E2‐PePHD region of hepatitis C virus type 1b and correlation with the response to combination therapy with interferon and ribavirin
summary. Nonstructural 5A (NS5A) and the second envelope (E2) proteins of hepatitis C virus (HCV) have the potential to block interferon (IFN)‐induced RNA‐dependent protein kinase (PKR) and mayExpand
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Combining the Capilia TB assay with smear morphology for the identification of Mycobacterium tuberculosis complex.
SETTING Many hospitals in Taiwan use the fully automated BACTEC Mycobacterial Growth Indicator Tube (MGIT) 960 system to identify mycobacteria in clinical specimens, while the labour-intensive BDExpand
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Regulation of cytokine expression in human plasmacytoid dendritic cells by prostaglandin I2 analogues
Plasmacytoid dendritic cells (pDCs) are critical in controlling adaptive immunity, but the mechanisms governing cytokine expression remain incompletely defined. Analogues of prostaglandin (PG)I2,Expand
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Multiple genetic and epigenetic biomarkers for lung cancer detection in cytologically negative sputum and a nested case–control study for risk assessment
The purpose of this study was to define a biomarker panel for detection of cancer cells in cytologically negative sputum and to evaluate the panel for assessment of lung cancer risk. We examined 19Expand
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HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms.
OBJECTIVE Kawasaki disease (KD) is a pediatric systemic vasculitis of unknown cause for which a genetic influence is supposed. The purpose of this study was to identify possible genetic variants inExpand
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The incidence and predictors of HBV relapse after cessation of tenofovir therapy in chronic hepatitis B patients
This study investigates the incidences and predictors of hepatitis B virus (HBV) relapse after tenofovir disoproxil fumarate (TDF) therapy in hepatitis B e antigen (HBeAg)‐positive and ‐negativeExpand
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Hepatitis B surface antigen loss and clinical outcomes between HBeAg‐negative cirrhosis patients who discontinued or continued nucleoside analogue therapy
We investigated the incidence and predictors of post‐treatment hepatitis B virus (HBV) relapse and hepatitis B surface antigen (HBsAg) loss. After cessation of nucleoside analogue (NA) treatment inExpand
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A tryptophan metabolite, kynurenine, promotes mast cell activation through aryl hydrocarbon receptor
Tryptophan metabolites have been suggested to play a role in immune modulation, wherein those have recently been shown to be endogenous ligands of aryl hydrocarbon receptor (AhR; a unique cellularExpand
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