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Multimodel inference in ecology and evolution: challenges and solutions
TLDR
A number of practical obstacles to model averaging complex models are highlighted and it is hoped that this approach will become more accessible to those investigating any process where multiple variables impact an evolutionary or ecological response. Expand
Episodic Positive Selection in the Evolution of Avian Toll-Like Receptor Innate Immunity Genes
TLDR
Evidence is provided that episodic positive selection has played an important role in the evolution of most avian TLRs, consistent with the role of these loci in pathogen recognition and a mechanism of host-pathogen coevolution. Expand
The imprecision of heterozygosity‐fitness correlations hinders the detection of inbreeding and inbreeding depression in a threatened species
TLDR
It is argued that pedigree methods remain the most effective method of quantifying inbreeding in wild populations, particularly those that have gone through severe bottlenecks, and that even relatively large numbers of microsatellites may give poor precision for estimating individual genome‐wide heterozygosity. Expand
Heterozygosity–fitness correlations and their relevance to studies on inbreeding depression in threatened species
TLDR
Differences between large, outbred populations and bottlenecked populations may affect both the ability to detect inbreeding depression in threatened species, and the interpretation of the underlying mechanisms for observed heterozygosity–fitness relationships. Expand
SEVERE INBREEDING DEPRESSION AND NO EVIDENCE OF PURGING IN AN EXTREMELY INBRED WILD SPECIES—THE CHATHAM ISLAND BLACK ROBIN
TLDR
Although the black robin demographic history provided ideal conditions for genetic purging, the results show no clear evidence of purging in the major life‐history trait of juvenile survival, and confirm that continued high levels of contemporary inbreeding in a historically inbred population could lead to additional severe inbreeding depression. Expand
Variation at Innate Immunity Toll-Like Receptor Genes in a Bottlenecked Population of a New Zealand Robin
TLDR
The levels of TLR diversity that are observed are sufficient to justify their further use in addressing conservation genetic questions, even in bottlenecked populations. Expand
Inbreeding depression accumulation across life-history stages of the endangered Takahe.
TLDR
The results indicate that "purged" populations can still exhibit substantial inbreeding depression, especially when small but negative fitness effects accumulate across the species' life history, and illustrate the importance of measuring the effects of inbreeding across the full life-history continuum. Expand
Characterization of MHC class II B polymorphism in bottlenecked New Zealand saddlebacks reveals low levels of genetic diversity
TLDR
Next generation sequencing is used to investigate MHC class II B diversity in two sister taxa of New Zealand birds, finding strong evidence for historic balancing selection in peptide-binding regions of putative alleles and a cluster combining non-classical loci and pseudogene sequences from both species, although no sequences were shared between the species. Expand
Simulating retention of rare alleles in small populations to assess management options for species with different life histories.
TLDR
The amount of immigration needed generally decreased with an increase in carrying capacity, survival, or reproductive output and increased as individual variation in reproductive success increased, indicating the importance of accurately quantifying these parameters to predict the effects of management. Expand
Managing genetic diversity in threatened populations : a New Zealand perspective
Genetic diversity allows a population to adapt genetically to a changing environment or to buffer it against stochastic events such as harsh weather or disease outbreaks. Genetic diversity isExpand
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