Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study.
A risk stratification schema can establish the risk of chemotherapy toxicity in older adults and Geriatric assessment variables independently predicted therisk of toxicity.
Participation in cancer clinical trials: race-, sex-, and age-based disparities.
Although the total number of trial participants increased during the study period, the representation of racial and ethnic minorities decreased and were less likely to enroll in cooperative group cancer trials than were whites, men, and younger patients, respectively.
Scope and impact of financial conflicts of interest in biomedical research: a systematic review.
Original, quantitative studies on the extent, impact, and management of financial conflicts of interest in biomedical research are reviewed to show a statistically significant association between industry sponsorship and pro-industry conclusions.
Are Racial and Ethnic Minorities Less Willing to Participate in Health Research?
These findings, based on the research enrollment decisions of over 70,000 individuals, the vast majority from the US, suggest that racial and ethnic minorities in the US are as willing as non-Hispanic whites to participate in health research.
The relation between funding by the National Institutes of Health and the burden of disease.
- C. Gross, G. Anderson, N. Powe
- Medicine, Political ScienceNew England Journal of Medicine
- 17 June 1999
A cross-sectional study comparing estimates of disease-specific funding in 1996 with data on six measures of the burden of disease found that the acquired immunodeficiency syndrome, breast cancer, diabetes mellitus, and dementia all received relatively generous funding, regardless of which measure was used as the basis for calculating support.
Recruiting Vulnerable Populations into Research: A Systematic Review of Recruitment Interventions
Further work with greater methodologic rigor is needed to identify evidence-based strategies for increasing minority enrollment in research studies; community outreach, as an isolated strategy, may be less successful than other strategies.
Representation of the elderly, women, and minorities in heart failure clinical trials.
Comparing the characteristics of patients in heart failure (HF) RCTs with those of patients with HF in the community, and to document these trends over time, did not find a significant improvement in the representation of the trials.
Racial and Ethnic Disparities in Population-Level Covid-19 Mortality
- C. Gross, U. Essien, S. Pasha, Jacob R. Gross, Shi-Yi Wang, M. Nunez-Smith
- MedicineJournal of general internal medicine
- 11 May 2020
The importance of adjusting for age differences across population groups to prevent underestimating disparities in younger population groups is demonstrated and is necessary to address factors contributing to inequity in Covid-19 mortality.
Use of hospital-based acute care among patients recently discharged from the hospital.
It is found that among the highest volume discharges, the most common reason patients returned to the ED was always related to their index hospitalization, and improving care transitions should focus not only on decreasing readmissions but also on ED visits.
Risk Prediction Model for Heart Failure and Cardiomyopathy After Adjuvant Trastuzumab Therapy for Breast Cancer
- Ghideon Ezaz, J. Long, C. Gross, Jersey Chen
- MedicineJournal of the American Heart Association…
- 3 January 2014
A 7‐factor risk score was able to stratify 3‐year risk of HF/CM after trastuzumab between the lowest and highest risk groups by more than 2‐fold in a Medicare population.