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The Neurometabolic Cascade of Concussion.
OBJECTIVE: To review the underlying pathophysiologic processes of concussive brain injury and relate these neurometabolic changes to clinical sports-related issues such as injury to the developingExpand
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Consensus statement on concussion in sport—the 5th international conference on concussion in sport held in Berlin, October 2016
The 2017 Concussion in Sport Group (CISG) consensus statement is designed to build on the principles outlined in the previous statements1–4 and to develop further conceptual understanding ofExpand
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The molecular pathophysiology of concussive brain injury.
Concussion or mild traumatic brain injury (mTBI) is a condition that affects hundreds of thousands of patients worldwide. Understanding the pathophysiology of this disorder can help manage its acuteExpand
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Summary of evidence-based guideline update: Evaluation and management of concussion in sports
Objective: To update the 1997 American Academy of Neurology (AAN) practice parameter regarding sports concussion, focusing on 4 questions: 1) What factors increase/decrease concussion risk? 2) WhatExpand
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The new neurometabolic cascade of concussion.
Since the original descriptions of postconcussive pathophysiology, there has been a significant increase in interest and ongoing research to study the biological underpinnings of concussion. TheExpand
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The New Neurometabolic Cascade of Concussion.
Objective: To review the underlying pathophysiologic processes of concussive brain injury and relate these neurometabolic changes to clinical sports-related issues such as injury to the developingExpand
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The pathophysiology of traumatic brain injury at a glance
Traumatic brain injury (TBI) is defined as an impact, penetration or rapid movement of the brain within the skull that results in altered mental state. TBI occurs more than any other disease,Expand
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Glutamate and GABA Imbalance Following Traumatic Brain Injury
Traumatic brain injury (TBI) leads to multiple short- and long-term changes in neuronal circuits that ultimately conclude with an imbalance of cortical excitation and inhibition. Changes inExpand
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Concussive Brain Injury Enhances Fear Learning and Excitatory Processes in the Amygdala
BACKGROUND Mild traumatic brain injury (cerebral concussion) results in cognitive and emotional dysfunction. These injuries are a significant risk factor for the development of anxiety disorders,Expand
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The Molecular Pathophysiology of Concussive Brain Injury - an Update.
Concussion, or mild traumatic brain injury (TBI), affects millions of patients worldwide. Understanding the pathophysiology of TBI can help manage its repercussions. The brain is significantlyExpand
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