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The role of fatty acids in the development and progression of nonalcoholic fatty liver disease.
Nonalcoholic fatty liver disease (NAFLD) has emerged as a serious obesity-related disorder. NAFLD encompasses a wide spectrum of hepatic derangements ranging from a surfeit of fat in the liverExpand
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Greater rate of decline in maximal aerobic capacity with age in endurance-trained than in sedentary men.
To determine the relation between habitual endurance exercise status and the age-associated decline in maximal aerobic capacity [i.e., maximal O(2) consumption (Vo(2 max))] in men, we performed aExpand
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Fatness Is a Better Predictor of Cardiovascular Disease Risk Factor Profile Than Aerobic Fitness in Healthy Men
Background—The prevalence of cardiovascular disease (CVD) is partly attributable to an inactive and/or overweight population. However, the independent association of body fatness and aerobic fitnessExpand
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Habitual physical activity differentially affects acute and short-term energy intake regulation in young and older adults
Background:Energy intake (EI) regulation is impaired in older adults, but it is not known if habitual physical activity affects accuracy of EI regulation in older compared with youngExpand
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Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease.
The underlying causes of nonalcoholic fatty liver disease (NAFLD) are unclear, although recent evidence has implicated the endoplasmic reticulum (ER) in both the development of steatosis andExpand
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Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow.
This study determined the effects of 28 days of oral creatine ingestion (days 1 to 5 = 20g/d; [5 g 4 times daily]: days 6 to 28 = 10 g/d; [5 g twice daily]) alone and with resistance training (5Expand
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Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death.
Prolonged endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) have been linked to apoptosis via several mechanisms, including increased expression of C/EBPExpand
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The gut microbiota at the intersection of diet and human health
Diet affects multiple facets of human health and is inextricably linked to chronic metabolic conditions such as obesity, type 2 diabetes, and cardiovascular disease. Dietary nutrients are essentialExpand
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Effects of 8 weeks of creatine supplementation on exercise performance and fat-free weight in football players during training
While the role of creatine in preventing muscle (peripheral) fatigue for high performance athletes is well understood, its biochemical role in prevention of mental (central) fatigue is not. CreatineExpand
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Fatty acids and the endoplasmic reticulum in nonalcoholic fatty liver disease.
Nonalcoholic fatty liver disease (NAFLD) represents a burgeoning public health concern in westernized nations. The obesity-related disorder is associated with an increased risk of cardiovascularExpand
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