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Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome…
- A. Arlt, S. Sebens, H. Schäfer
- Biology, ChemistryOncogene
- 1 October 2013
TLDR
Derivation of oocyte-like cells from a clonal pancreatic stem cell line.
- S. Danner, J. Kajahn, C. Geismann, E. Klink, C. Kruse
- BiologyMolecular human reproduction
- 2007
TLDR
Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer.
- C. Geismann, M. Morscheck, S. Müerköster
- Biology, MedicineCancer research
- 15 May 2009
TLDR
Cytoprotection “gone astray”: Nrf2 and its role in cancer
- C. Geismann, A. Arlt, S. Sebens, H. Schäfer
- Biology, MedicineOncoTargets and therapy
- 26 August 2014
TLDR
Identification and characterization of two functional variants in the human longevity gene FOXO3
- F. Flachsbart, J. Dose, A. Nebel
- BiologyNature Communications
- 12 December 2017
TLDR
L1CAM expression in endometrial carcinomas is regulated by usage of two different promoter regions
- M. Pfeifer, Uwe Schirmer, C. Geismann, H. Schäfer, S. Sebens, P. Altevogt
- BiologyBMC Molecular Biology
- 27 August 2010
TLDR
Modulation of Nuclear Factor E2-related Factor-2 (Nrf2) Activation by the Stress Response Gene Immediate Early Response-3 (IER3) in Colonic Epithelial Cells
- I. Stachel, C. Geismann, H. Schäfer
- Biology, MedicineThe Journal of Biological Chemistry
- 5 December 2013
TLDR
Binding of the transcription factor Slug to the L1CAM promoter is essential for transforming growth factor-β1 (TGF-β)-induced L1CAM expression in human pancreatic ductal adenocarcinoma cells.
- C. Geismann, A. Arlt, H. Schäfer
- BiologyInternational journal of oncology
- 24 November 2010
TLDR
alpha5-integrin is crucial for L1CAM-mediated chemoresistance in pancreatic adenocarcinoma.
- Susanne Sebens Müerköster, J. Kötteritzsch, H. Schäfer
- BiologyInternational journal of oncology
- 2009
TLDR
Role of CCL20 mediated immune cell recruitment in NF-κB mediated TRAIL resistance of pancreatic cancer.
- C. Geismann, F. Grohmann, A. Arlt
- BiologyBiochimica et biophysica acta. Molecular cell…
- 1 May 2017
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