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High predictivity of galactosyl-hydroxylysine in urine as an indicator of bone metastases from breast cancer.
We measured the urinary excretion of galactosyl-hydroxylysine (GH) and hydroxyproline in two groups of women with breast cancer, with (M+, n = 24) and without (Mo, n = 30) clinical, scintigraphic, or… Expand
Biochemical markers for detecting bone metastases in patients with breast cancer.
- L. Moro, C. Gazzarrini, D. Crivellari, E. Galligioni, R. Talamini, B. de Bernard
- Biology, Medicine
- Clinical chemistry
In a selected population of patients affected by metastases on the basis of scintigraphic examination, the only marker able to predict metastases was galactosyl-hydroxylysine, and the efficiency of the markers was assessed by a double statistical analysis. Expand
Possible mechanism of inhibition of cartilage alkaline phosphatase by insulin
- C. Gazzarrini, N. Stagni, P. Pollesello, P. D'andrea, B. Bernard
- Acta diabetologia latina
- 1 October 1989
Data suggest direct interaction between the alkaline phosphatase and insulin molecules, involving either disulfide cross linkages or the metal chelating activity of insulin. Expand
Urinary β-1-galactosyl-0-hydroxylysine (GH) as a marker of collagen turnover of bone
- L. Moro, R. S. Mucelli, C. Gazzarrini, C. Modricky, F. Marotti, B. Bernard
- Chemistry, Medicine
- Calcified Tissue International
- 1 February 1988
Measurement of GH in urine provides a simple and noninvasive method for the evaluation of the extent of bone resorption in large groups of subjects and appears to be more specific than urinary hydroxyproline excretion. Expand