C. Frith

Publications1,185
h-index67
Citations31,032
Highly Influential Citations1,263
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A differential neural response in the human amygdala to fearful and happy facial expressions
TLDR
Direct in vivo evidence of a differential neural response in the human amygdala to facial expressions of fear and happiness is reported, providing direct evidence that the humangdala is engaged in processing the emotional salience of faces, with a specificity of response to fearful facial expressions. Expand
Comparing Functional (PET) Images: The Assessment of Significant Change
TLDR
This report describes an approach that may partially resolve the uncertainty in assessing the significance of statistical parametric maps and models the SPM as a stationary stochastic process. Expand
Functional Connectivity: The Principal-Component Analysis of Large (PET) Data Sets
TLDR
The results suggest that the variance in neurophysiological measurements, introduced experimentally, was accounted for by two independent principal components and highlighted an intentional brain system seen in previous studies of verbal fluency. Expand
A neuromodulatory role for the human amygdala in processing emotional facial expressions.
TLDR
Functional neuroimaging confirmed that the amygdala and some of its functionally connected structures mediate specific neural responses to fearful expressions and demonstrated that amygdalar responses predict expression-specific neural activity in extrastriate cortex. Expand
Dissociable neural responses to facial expressions of sadness and anger.
TLDR
Functional neuroimaging results provide evidence for dissociable, but interlocking, systems for the processing of distinct categories of negative facial expression. Expand
Dyslexia: Cultural Diversity and Biological Unity
TLDR
It is concluded that there is a universal neurocognitive basis for dyslexia and that differences in reading performance among dyslexics of different countries are due to different orthographies. Expand
Investigations of the functional anatomy of attention using the stroop test
TLDR
The results provide evidence for the involvement of anterior right hemisphere and medial frontal structures in attentional tasks but also indicate that time effects can confound task specific activations. Expand
Characterizing Evoked Hemodynamics with fMRI
TLDR
Using this approach, the anterior cingulate differentiates, in terms of its response, between two motor tasks that did and did not require sustained attention, and it is suggested that these demonstration results point to the possibility of making greater use of the temporal resolution afforded by fast fMRI techniques. Expand
Willed action and the prefrontal cortex in man: a study with PET
TLDR
Willed acts in the two response modalities studied (speaking a word, or lifting a finger) were associated with increased blood flow in the dorsolateral prefrontal cortex (Brodmann area 46) and decreases in blood flow were also associated, but the location of these decreases was modality dependent. Expand
Schizophrenia: a disconnection syndrome?
TLDR
The argument is that some schizophrenic phenomena are best understood in terms of abnormal interactions between different areas, not only at the levels of physiology and functional anatomy, but at the level of cognitive and sensorimotor functioning. Expand
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