C. Franzen

Publications91
h-index25
Citations1,848
Highly Influential Citations93
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Microsporidiosis: human diseases and diagnosis.
Microsporidia are considered opportunistic pathogens in humans because they are most likely to cause diseases if the immune status of a host is such that the infection cannot be controlled. A wide… Expand
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Transfer of the Members of the Genus Brachiola (Microsporidia) to the Genus Anncaliia Based on Ultrastructural and Molecular Data
ABSTRACT. Two microsporidian genera, Anncaliia Issi, Krylova, & Nicolaeva 1993 and Brachiola Cali et al. 1998 , possess a Nosema‐type life cycle and unique cell surface ornamentations, which include… Expand
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Morphological and Molecular Investigations of Tubulinosema ratisbonensis gen. nov., sp. nov. (Microsporidia: Tubulinosematidae fam. nov.), a Parasite Infecting a Laboratory Colony of Drosophila…
Abstract. A new species of microsporidia from Drosophila melanogaster was investigated by light and electron microscopy and by ribosomal RNA (rRNA) sequencing. This microsporidium and the previously… Expand
  • 51
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Cryptosporidia and microsporidia--waterborne diseases in the immunocompromised host.
Cryptosporidia and microsporidia are emerging parasitic pathogens in immunocompetent and immunocompromised individuals. Cryptosporidium infects several wild and domestic animals that excrete oocysts… Expand
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Taxonomic position of the human intestinal protozoan parasite Isospora belli as based on ribosomal RNA sequences
Abstract The taxonomic positions of Isospora belli and other members of the genus Isospora are controversial. We determined the small-subunit ribosomal RNA of I. belli and used this sequence in… Expand
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Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV‐infected patients
Objective:To determine the rate of virological treatment failure with protease inhibitor therapy in unselected patients and to assess underlying risk factors. Design and setting:Retrospective study… Expand
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Microsporidia: how can they invade other cells?
  • C. Franzen
  • Biology, Medicine
  • Trends in parasitology
  • 1 June 2004
Microsporidia are obligate intracellular eukaryotic parasites that have a distinctive mechanism for infecting host cells. Microsporidian spores contain a long coiled polar tube that extrudes from the… Expand
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A Powerful DNA Extraction Method and PCR for Detection of Microsporidia in Clinical Stool Specimens
ABSTRACT The diagnosis of intestinal microsporidiosis has traditionally depended on direct visualization of the parasite in stool specimens or intestinal biopsy samples by light and/or electron… Expand
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Cell invasion and intracellular fate of Encephalitozoon cuniculi (Microsporidia).
Microsporidia are obligate intracellular parasites that utilize a unique mechanism to infect host cells, which is one of the most sophisticated infection mechanisms in biology. Microsporidian spores… Expand
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Cytokine and nitric oxide responses of monocyte-derived human macrophages to microsporidian spores.
Microsporidia are obligate intracellular parasites that emerged as opportunistic pathogens since the onset of the AIDS pandemic. They are capable of disseminating through the body using macrophages… Expand
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