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Distinct genetic influences on cortical surface area and cortical thickness.
- M. Panizzon, C. Fennema-Notestine, +13 authors W. Kremen
- Psychology, Medicine
- Cerebral cortex
- 1 November 2009
Neuroimaging studies examining the effects of aging and neuropsychiatric disorders on the cerebral cortex have largely been based on measures of cortical volume. Given that cortical volume is a… Expand
Influence of patients' requests for direct-to-consumer advertised antidepressants: a randomized controlled trial.
CONTEXT Direct-to-consumer (DTC) advertising of prescription drugs in the United States is both ubiquitous and controversial. Critics charge that it leads to overprescribing, while proponents counter… Expand
Motivation and personality: Methodological considerations: steps in research employing content analysis systems
Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders
Personality is influenced by genetic and environmental factors and associated with mental health. However, the underlying genetic determinants are largely unknown. We identified six genetic loci,… Expand
Genetic and environmental influences on the size of specific brain regions in midlife: The VETSA MRI study
- W. Kremen, E. Prom-Wormley, +16 authors C. Fennema-Notestine
- Computer Science, Psychology
- 15 January 2010
The impact of genetic and environmental factors on human brain structure is of great importance for understanding normative cognitive and brain aging as well as neuropsychiatric disorders. However,… Expand
Pathways to Dementia Diagnosis: Evidence for Cross-Ethnic Differences
SummaryThe diagnosis of dementia often occurs well after the onset of the disease. Studies of help-seeking behavior may help illuminate why delays occur. Specific Aims(1) To describe pathways to… Expand
A 35-year longitudinal assessment of cognition and midlife depression symptoms: the Vietnam Era Twin Study of Aging.
- C. Franz, M. Lyons, +8 authors W. Kremen
- Medicine, Psychology
- The American journal of geriatric psychiatry…
- 1 June 2011
OBJECTIVE To determine whether early adult cognitive ability is a risk factor for depressive symptoms in midlife and how genetic and environmental influences explain the association and to examine… Expand
Hierarchical Genetic Organization of Human Cortical Surface Area
Building the Brain Brain connectivity is often described as a network of discrete independent cables analogous to a switchboard, but how is the physical structure of the brain constructed (see the… Expand
Salivary cortisol and prefrontal cortical thickness in middle-aged men: A twin study
Although glucocorticoid receptors are highly expressed in the prefrontal cortex, the hippocampus remains the predominant focus in the literature examining relationships between cortisol and brain. We… Expand
A comparison of heritability maps of cortical surface area and thickness and the influence of adjustment for whole brain measures: a magnetic resonance imaging twin study.
- L. Eyler, Chi-Hua Chen, +14 authors W. Kremen
- Twin research and human genetics : the official…
- 1 June 2012
Understanding the genetic and environmental contributions to measures of brain structure such as surface area and cortical thickness is important for a better understanding of the nature of… Expand