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Differential distribution of retinoic acid synthesis in the chicken embryo as determined by immunolocalization of the retinoic acid synthetic enzyme, RALDH-2.
The immunolocalization of this enzyme (RALDH-2-IR) is reported in stage 6-29 chicken embryos to indicate dynamic and discrete patterns of retinoic acid synthesis in the embryo, particularly within the somitic mesderm, lateral mesoderm, kidney, heart, and spinal motor neurons. Expand
Density of somatic innervation on mammalian autonomic ganglion cells is inversely related to dendritic complexity and preganglionic convergence
  • C. Forehand
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 1 December 1985
Evidently the somatic membrane becomes a less favorable site for synapse formation as dendritic complexity and the number of inputs increase, which may reflect competitive interactions between the axons innervating individual ganglion cells. Expand
Galanin‐like innervation of rat submandibular and sublingual salivary glands: Origin and effect on acinar cell membranes
Results indicate that the galanin‐like innervation of rat salivary glands is derived from parasympathetic nerves to the glands, and that galan in‐immunoreactive sensory neurons in the trigeminal ganglion do not innervate the submandibular or sublingual gland. Expand
Segmental restriction and target specificity of bullfrog preganglionic neurons that exhibit galanin-like immunoreactivity.
Examination of galanin-like peptide immunoreactivity in bullfrog sympathetic preganglionic neurons and the peripheral target organs affected by these neurons demonstrated that most GAL-IR neurons project via splanchnic nerves to innervate the adrenal gland, which receives a dense plexus of Gal-IR fibers surrounding chromaffin cells. Expand
Expression and regulation of the retinoic acid synthetic enzyme RALDH‐2 in the embryonic chicken wing
It is proposed that locally synthesized RA may be involved in aspects of wing tissue specification, including cartilage condensation and outgrowth, skeletal muscle differentiation, and recruitment of smooth muscle cells to the vasculature. Expand
Mutation of low affinity nerve growth factor receptor gene is associated with the hypertensive phenotype in spontaneously hypertensive inbred rat strains
The results support the original hypothesis that the mutated LNGFR gene is linked to hypertension, since the mutation had co-segregated with the hypertensive trait, and not hyperactivity trait of SHR. Expand
Morphology of two classes of target‐specific bullfrog sympathetic preganglionic neurons
These experiments took advantage of the unique ability to define target‐specific sympa‐thetic preganglionic neurons in the bullfrog spinal cord in order to examine the morphologies of differentExpand
An in ovo chicken model to study the systemic and localized teratogenic effects of valproic acid.
Results indicate that at least one mechanism for the teratogenicity of VPA involves a direct effect on developing tissue, and implies that this effect may be mediated by disruption of genes that regulate pattern formation. Expand
Anatomical and behavioral recovery from the effects of spinal cord transection: dependence on metamorphosis in anuran larvae
Results show that spinal cord continuity is readily restored in tadpoles subjected to spinal cord transection, but nerve fibers crossing the site of injury end within 1 to 2 mm of the lesion site, and these same animals as juvenile frogs show recovery of behaviors that are dependent upon connections to supraspinal regions. Expand
Spinal cord development in anuran larvae: I. Primary and secondary neurons
Primary motoneurons that innervate the tadpole tail were not found in the adult, although those innervating thoracic musculature persisted, as did at least somePrimary neurons projecting to other spinal segments or brainstem are replaced or maintained through metamorphosis depending on their class and location. Expand