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Electrospun nanofibrous polymeric scaffold with targeted drug release profiles for potential application as wound dressing.
We have successfully fabricated a dual drug release electrospun scaffold containing an anesthetic, lidocaine, and an antibiotic, mupirocin. Two drugs with different lipophilicities were electrospunExpand
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Microfibrous substrate geometry as a critical trigger for organization, self‐renewal, and differentiation of human embryonic stem cells within synthetic 3‐dimensional microenvironments
Substrates used to culture human embryonic stem cells (hESCs) are typically 2‐dimensional (2‐D) in nature, with limited ability to recapitulate in vivo‐like 3‐dimensional (3‐D) microenvironments. WeExpand
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Minute changes in composition of polymer substrates produce amplified differences in cell adhesion and motility via optimal ligand conditioning.
We explored the interplay between substratum chemistry of polymeric materials and surface-adsorbed ligand concentration (human plasma fibronectin) in the control of cell adhesion and cell motility.Expand
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Constructing Human Skin Equivalents on Porcine Acellular Peritoneum Extracellular Matrix for In Vitro Irritation Testing.
The irritancy of topical products has to be investigated to ensure the safety and compliance. Although several reconstructed human epidermal models have been adopted by the Organization for EconomicExpand
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An Ellipsoidal Droplet Model For Dilute Emulsions: Application To ComplexMixing Flows
A compact droplet model and numerical simulation are used to examine the behavior of multiphase fluids in complex mixing flows. The two-dimensional, timeperiodic fluid between eccentric cylinders isExpand
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