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Human oocyte cryopreservation: new perspectives regarding oocyte survival.
A significantly higher survival rate was obtained when the oocytes were cryopreserved in the presence of a doubled sucrose concentration in the freezing solution and the survival ratewas even higher when the Sucrose concentration was tripled. Expand
Sperm DNA fragmentation: paternal effect on early post-implantation embryo development in ART.
Sperm DNA fragmentation seems to affect embryo post-implantation development in ICSI procedures: high sperm DNA fragmentation can compromise 'embryo viability', resulting in pregnancy loss. Expand
Clinical outcome of oocyte cryopreservation after slow cooling with a protocol utilizing a high sucrose concentration.
The data indicate that although the combination of slow cooling and high sucrose concentration ensures high rates of oocyte survival, it is not sufficient to guarantee a high standard of clinical efficiency. Expand
Differential sucrose concentration during dehydration (0.2 mol/l) and rehydration (0.3 mol/l) increases the implantation rate of frozen human oocytes.
Increased oocyte survival rates can be achieved by moderately high sucrose concentrations in the freezing and thawing solutions, which ensures elevated success rates in terms of fertilization, embryo development and clinical outcome. Expand
Fertility and obstetric outcome after laparoscopic myomectomy of large myomata: a randomized comparison with abdominal myomectomy.
The purpose of this study was to compare, in infertile patients, the efficacy of laparoscopic myomectomy versus abdominal myomectomy, in restoring fertility and to evaluate the obstetric outcomes.Expand
Uterine contractility during the menstrual cycle.
Although UC patterns favouring sperm transport appear regulated by oestradiol, uterine quiescence and the dominance of convergent UC prevailing at the time of implantation are linked to progesterone, the hormonal dependence of uterine contractility is emphasized. Expand
Clinical relevance of sperm DNA damage in assisted reproduction.
Assessment of sperm DNA damage appears to be a potential tool for evaluating semen samples prior to their use in assisted reproduction, helping to select spermatozoa with intact DNA or with the least amount of DNA damage for use inassisted conception. Expand
Clinical experience and applications of oocyte cryopreservation
It is demonstrated that pregnancies can also be achieved when frozen eggs are fertilized by testicular and epididymal sperm and a program of oocyte cryopreservation for oncological patients has been initiated in this centre. Expand
Birth of a healthy female after intracytoplasmic sperm injection of cryopreserved human oocytes.
The combination of ICSI and oocyte cryopreservation is a new tool in assisted reproductive technology and achieves the first birth achieved after intracytoplasmic sperm injection (ICSI) ofcryopreserved human oocytes. Expand
Treatment of anovulation with pulsatile gonadotropin-releasing hormone: prognostic factors and clinical results in 600 cycles.
It is concluded that pGnRH is a highly effective ovulation induction method that is less successful in overweight patients and when high baseline LH, testosterone, and insulin levels are present and GnRH-A pretreatment improves pGNRH outcome in PCO and further lowers the incidence of multiple pregnancy. Expand