Uterine Artery Doppler Flow Velocity Waveforms in the Second Trimester for the Prediction of Preeclampsia and Fetal Growth Retardation
- R. North, C. Ferrier, D. Long, K. Townend, P. Kincaid‐Smith
- MedicineObstetrics and gynecology
- 1 March 1994
Although abnormal uterine artery Doppler is associated with an increased risk of preeclampsia and FGR, the positive predictive values do not support its introduction as a routine screening test in nulliparous women.
Simultaneous measurements of cardiac noradrenaline spillover and sympathetic outflow to skeletal muscle in humans.
The data suggest (a) that there are proportional interindividual differences in the strength of resting sympathetic activity to heart and skeletal muscle which are determined by a common mechanism and (b) that handgrip and mental stress are associated with differences in balance between sympathetic outflows to heartand skeletal muscle.
Frequency and severity of pain and symptom distress among patients with chronic kidney disease receiving dialysis.
Routine assessment of pain burden, pain management similar to that used in palliative care, and adequate analgesic use to treat specific dialysis-associated pain syndromes should be considered in guidelines.
Alfentanil Pharmacokinetics in Patients with Cirrhosis
- C. Ferrier, J. Marty, Y. Bouffard, J. Haberer, J. Levron, P. Duvaldestin
- Medicine, BiologyAnesthesiology
- 1 April 1985
It is suggested that the increase in the free fraction is caused by an alteration of binding sites of this protein in patients with cirrhosis, due to its delayed elimination and increased free fraction.
[Hypertensive disorders in pregnancy].
The prophylactic use of low-dose heparin, which has lead to a significant decreased incidence of preeclampsia in retrospective analysis, is now the object of a randomized, controlled trial in the authors' hospital.
Evidence for increased noradrenaline release from subcortical brain regions in essential hypertension
It is suggested that increased subcortical noradrenaline release is a possible cause of peripheral sympathetic activation in essential hypertension.
Dysregulation of atrial natriuretic factor in hypertension-prone man.
A new endocrine syndrome characterized by a relative plasma ANF deficiency during high sodium intake in some hypertension-prone humans is postulated and occurs as a familial disturbance and may potentially predispose to the development of hypertension.
Biochemical evidence of sympathetic hyperactivity in human hypertension.
- M. Esler, C. Ferrier, G. Lambert, G. Eisenhofer, H. Cox, G. Jennings
- Biology, MedicineHypertension
- 1 April 1991
Higher rates of norepinephrine spillover into the cerebrovascular circulation in patients with essential hypertension than in healthy subjects are found, suggesting that an underlying increase in central nervous system norpinephrine turnover may be the basis for the increased sympathetic outflow.
Atrial natriuretic peptide in man.
Although investigations in humans began only recently, information is rapidly expanding, and some observations on blood levels and effects of ANP in man are summarized.
Impaired contraction and relaxation in skin resistance arteries from patients with congestive heart failure.
- J. Angus, C. Ferrier, K. Sudhir, D. Kaye, G. Jennings
- Medicine, BiologyCardiovascular research
- 1 February 1993
The results suggest that in chronic congestive heart failure skin resistance arteries have impaired contraction responses probably independent of any receptor down regulation and the loss of endothelium dependent vasodilatation to acetylcholine suggests that EDRF release is impaired.