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Randomised study of screening for colorectal cancer with faecal-occult-blood test
- O. Kronborg, C. Fenger, J. Olsen, O. D. Jørgensen, O. Søndergaard
- MedicineThe Lancet
- 30 November 1996
The findings indicate that biennial screening by FOB tests can reduce CRC mortality, and the effect of the removal of more precursor adenomas in the screening-group participants than in controls on CRC incidence.
A prospective randomized study of follow‐up after radical surgery for colorectal cancer
- B. J. Kjeldsen, O. Kronborg, C. Fenger, O. D. Jørgensen
- MedicineThe British journal of surgery
- 1 May 1997
This study investigated whether survival is improved by frequent follow‐up examinations after curative surgery for colorectal cancer and found that the answer was yes.
Clinical Benefit of a Gluten-Free Diet in Type 1 Diabetic Children With Screening-Detected Celiac Disease
This population-based study showed the highest reported prevalence of Celiac disease in type 1 diabetes in Europe and patients with celiac disease showed clinical improvements with a GFD.
Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair
This is the first simple laboratory test which can be performed routinely on all CRCs and will provide a method for selecting patients who should be investigated for HNPCC, offered long term follow up, and who may not respond to standard chemotherapy regimens.
A randomised study of screening for colorectal cancer using faecal occult blood testing: results after 13 years and seven biennial screening rounds
The persistent reduction in mortality from CRC in a biennial screening program with Hemoccult-II, and a reduction in RR to less than 0.70 in those adhering to the programme, support attempts to introduce larger scale population screening programmes.
Randomized study of biennial screening with a faecal occult blood test: results after nine screening rounds
- O. Kronborg, O. D. Jørgensen, C. Fenger, M. Rasmussen
- MedicineScandinavian journal of gastroenterology
- 1 January 2004
Efficacy in those screened supports the introduction of countrywide screening in Denmark, but it must be ascertained that acceptability, proportion of early CRC and logistics all reach the same standard as in the randomized trial.
Variants of squamous cell carcinoma of the anal canal and perianal skin and their relation to human papillomaviruses.
In both women and men, anal canal cancers contained hrHPVs clearly more often than did perianal skin cancers, and increasing hrHPV positivity was seen with higher localization in the anal canal.
Recurrence and survival after mesorectal excision for rectal cancer
- S. Bülow, I. Christensen, H. Harling, O. Kronborg, C. Fenger, H. Nielsen
- MedicineThe British journal of surgery
- 1 August 2003
The results of a prospective Danish study with a historical control group showing Mesorectal excision for rectal cancer has resulted in local recurrence rates of 3–11 per cent compared with up to 38 per cent after conventional methods are presented.
Colorectal Adenoma Characteristics as Predictors of Recurrence
- C. Bonithon-Kopp, F. Piard, +4 authors J. Faivre
- MedicineDiseases of the colon and rectum
- 1 March 2004
Follow-up colonoscopies in patients with adenomas should include careful examination of the proximal colon, and the time interval between follow-up examinations could probably be extended beyond three years in patients who have only one or two distalAdenomas.
Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer.
- W. Kang, O. Nielsen, C. Fenger, G. Leslie, U. Holmskov, K. Reid
- Biology, MedicineCarcinogenesis
- 1 June 2005
The results suggest that the transient induction of DMBT1 is apparently specific at an early stage of gastric epithelial differentiation-like process, when it may play a role in cell fate decision.