General imprinting status is stable in assisted reproduction-conceived offspring.
- C. Feng, Shen Tian, He-feng Huang
- BiologyFertility and Sterility
- 1 December 2011
Identification of a mutation in GDF9 as a novel cause of diminished ovarian reserve in young women.
- Ting-ting Wang, Zhang-Hong Ke, He-feng Huang
- BiologyHuman Reproduction
- 1 September 2013
The results may provide new insights into the pathophysiological mechanisms of early-onset DOR and larger studies in varying populations may validate the role of GDF9 mutation in young women with DOR.
High maternal serum estradiol environment in the first trimester is associated with the increased risk of small-for-gestational-age birth.
- Xiao-Ling Hu, C. Feng, He-feng Huang
- MedicineJournal of Clinical Endocrinology and Metabolism
- 28 February 2014
The maternal high-E2 environment in the first trimester is correlated with increased risks of LBW and SGA, and Evaluation of serum E2 before ET should be adopted to reduce the possibility of high E2 exposure to gamete/embryo.
Assisted reproductive technology may increase clinical mutation detection in male offspring.
- C. Feng, Li-quan Wang, M. Dong, He-feng Huang
- MedicineFertility and Sterility
- 1 July 2008
Decreased expression of endometrial vessel AQP1 and endometrial epithelium AQP2 related to anovulatory uterine bleeding in premenopausal women
- C. Feng, Chao-chao Sun, Ting-ting Wang, Rong-huan He, J. Sheng, He-feng Huang
- Medicine, BiologyMenopause
- 1 July 2008
It is indicated that cyclic expression of endometrial AQP1/AQP2 correlated with steroid hormone levels may be essential to normal endometrium function and decreased AQP 1/A QP2 expression in endometrian vessels or epithelium may be involved in the occurrence of anovulatory uterine bleeding.
Role of anti-Müllerian hormone and testosterone in follicular growth: a cross-sectional study
Since DOR and PCOS are manifested with insufficient AMH and excessive AMH respectively, it is suggested that total testosterone correlated with AMH closely and plays an important role in follicular growth.
The Association between Polymorphism of INSR and Polycystic Ovary Syndrome: A Meta-Analysis
- C. Feng, P. Lv, Shi-Wen Jiang
- BiologyInternational Journal of Molecular Sciences
- 22 January 2015
A meta-analysis suggests no significant correlation between rs1799817/rs2059806 SNPs and susceptibility of PCOS, while rs2059807 could be a promising candidate SNP that might be involved in the susceptibility ofPCOS.
Intrauterine exposure to hyperglycemia retards the development of brown adipose tissue
- Danqing Yu, P. Lv, He-feng Huang
- BiologyThe FASEB Journal
- 13 February 2019
The results provide the evidence for enduring inhibitory effects of intrauterine hyperglycemia on BAT development in offspring and associated with increased DNA methylation of the BAT specific genes in offspring, which support an epigenetic involvement.
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